Ammodesmidae are represented in western Africa by two species of a single genus, Ammodesmus Cook, 1896 (= Cenchrodesmus Cook, 1896, syn. n.). The type-species Ammodesmus granum Cook, 1896 (= Cenchrodesmus volutus Cook, 1896, syn. n.) is redescribed, based on neotype selection, as well as on additional samples, often containing numerous specimens, from Liberia, Guinea and the Ivory Coast. A new ...

Levosimendan enhances cardiac contractility via Ca(2+) sensitization and induces vasodilation through the activation of ATP-dependent K(+) and large-conductance Ca(2+)-dependent K(+) channels. However, the hemodynamic effects of levosimendan, as well as its metabolites, OR-1896 and OR-1855, relative to plasma concentrations achieved, are not well defined. Thus levosimendan, OR-1896, OR-1855, or...

Hugo von Hofmannsthal (1874-1929): uma breve apresentação Traduções: Início de primavera (1892) Tercetos (1895/1896) Segredo do mundo (1896) Balada da vida exterior Existem aqueles Dois O teu semblante estava pleno sonhos (1896)Os caminhos e os encontros

AIMS We recently published that the positive inotropic response (PIR) to levosimendan can be fully accounted for by phosphodiesterase (PDE) inhibition in both failing human heart and normal rat heart. To determine if the PIR of the active metabolite OR-1896, an important mediator of the long-term clinical effects of levosimendan, also results from PDE3 inhibition, we compared the effects of OR-...

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Jean Piaget was born in Neuchâtel, Switzerland, on August 9, 1896. His father, Arthur Piaget, was a professor of medieval literature with an interest in local history. His mother, Rebecca Jackson, was intelligent and energetic, but Jean found her a bit neurotic -an impression that he said led to his interest in psychology, but away from pathology! The oldest child, he was quite independent and ...

Cytochrome P450 (P450) function requires the interaction of P450 and NADPH-cytochrome P450 reductase (CPR) in membranes, and is frequently studied using reconstituted systems composed solely of phosphatidylcholine. There is increasing evidence that other endoplasmic reticulum (ER) lipids can affect P450 structure, activity, and interactions with CPR. Some of these lipid effects have been attrib...

In 1895, the German physicist, Wilhelm Conrad Röntgen (1845-1923), who was 50 years old by then, studied cathode rays with Crookes tubes. He was more precisely concerned with the penetration of the rays through the glass. At the time, it had already been established that cathode rays could pass through the tube wall and penetrate a few centimetres in the air. In the evening of November 8, durin...

We develop a theoretical model for a fluidic current source consisting of a via, a detour channel, and a push-up type micro-valve. The model accurately describes the non-linear behaviour of this type of device, which has been previously measured experimentally. We show how various structural parameters and material properties of the device influence the saturated flow rate and the minimum drivi...

BACKGROUND Levosimendan and its long-lived metabolite OR-1896 produce vasodilation in different types of vessels by activating ATP-sensitive (KATP) and other potassium channels. METHODS In the present study we applied intravital videomicroscopy to investigate the in situ effects of levosimendan and OR-1896 on the diameters of real resistance arterioles (rat cremaster muscle arterioles with di...