نتایج جستجو برای: 155

تعداد نتایج: 14701  

Journal: :Plastic and Reconstructive Surgery - Global Open 2020

1999
Shuhei Kinoshita Yoshikazu Yamamoto

The major purpose of our research is to study cooperative planning for multi-agent system in time-critical environment. The RoboCup simulator league is the most interesting target for our research. Each agent of the team 11monkeys is realized as an autonomous agent that has two sets of rules, namely state dependent rules and position speciied rules. We call the former dynamic role and the latte...

Journal: :Pediatric Critical Care Medicine 2018

2018
Yang Li Yanhong Duo Jiangang Bi Xiaowei Zeng Lin Mei Shiyun Bao Lisheng He Aijun Shan Yue Zhang Xiaofang Yu

Introduction MicroRNA-155 (miR-155) is an oncogenic microRNA, which is upregulated in many human cancers including colorectal cancer (CRC). Overexpression of miR-155 has been found to regulate several cancer-related pathways, and therefore, targeting miR-155 may be an effective strategy for cancer therapy. However, effective and safe delivery of anti-miR-155 to tumors remains challenging for th...

Journal: :Realidad: Revista de Ciencias Sociales y Humanidades 2020

2017
Carol M. Artlett Sihem Sassi-Gaha Jennifer L. Hope Carol A. Feghali-Bostwick Peter D. Katsikis

BACKGROUND Despite the important role that microRNAs (miRNAs) play in immunity and inflammation, their involvement in systemic sclerosis (SSc) remains poorly characterized. miRNA-155 (miR-155) plays a role in pulmonary fibrosis and its expression can be induced with interleukin (IL)-1β. SSc fibroblasts have activated inflammasomes that are integrally involved in mediating the myofibroblast phen...

2016
Izabella Slezak-Prochazka Joost Kluiver Debora de Jong Katarzyna Smigielska-Czepiel Gertrud Kortman Melanie Winkle Bea Rutgers Jasper Koerts Lydia Visser Arjan Diepstra Bart-Jan Kroesen Anke van den Berg

Several studies have indicated an important role for miR-155 in the pathogenesis of B-cell lymphoma. Highly elevated levels of miR-155 were indeed observed in most B-cell lymphomas with the exception of Burkitt lymphoma (BL). However, the molecular mechanisms that underlie the oncogenic role of miR-155 in B-cell lymphoma are not well understood. To identify the miR-155 targets relevant for B-ce...

2016
Sinae Kim Jin Hoi Song Seokho Kim Peng Qu Betty K. Martin Waheed S. Sehareen Diana C. Haines Pengnian C. Lin Shyam K. Sharan Suhwan Chang

The oncogenic role of microRNA-155 (miR-155) in leukemia is well established but its role in other cancers, especially breast cancer, is gradually emerging. In this study we examined the effect of mir-155 loss in a well-characterized spontaneous breast cancer mouse model where Brca1 and Trp53 are deleted by K14-Cre. miR-155 is known to be up-regulated in BRCA1-deficient tumors. Surprisingly, co...

2015
Krung Phiwpan Jie Guo Wei Zhang Tanyu Hu Bhargavi M. Boruah Jianhua Zhang Xuyu Zhou Sunil K. Ahuja

MicroRNA-155 (miR-155) plays significant role in various physiological processes involving both innate and adaptive immunity. miR-155 expression level changes dynamically during various immune responses. However, current approaches for miR-155 detection at the RNA level do not precisely reflect the real-time activity. Herein, we generated a transgenic mouse line (R26-DTR-155T) for determination...

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