Circulating lipoproteins may offer interesting properties as therapeutic carriers for cytokines and hormones, in terms of both stability and bio-distribution. The fusion of apolipoprotein A-I with interleukin-15 (IL-15) targets the latter to high-density lipoproteins (HDLs). The bioactivity of this chimera can be further enhanced by creating triple fusions with IL-15 receptor α domain involved ...

Paratesticular tumors are rare and often benign causes of scrotal masses. Intrascrotal angiolipomas are an uncommon paratesticular tumor that has seldom been reported in the literature. This report describes a 77 year old man who presented with a 15 cm extratesticular mass. The mass was removed due to increasing discomfort and specimen pathology confirmed it as an angiolipoma. This case highlig...

One artifact from my childhood in the 1960’s that I still remember vividly is the series of plastic slidingblock puzzles manufactured by The Roalex Company of Forest Hills, NY (no relation to the maker of fine timepieces). These consisted of a high-quality plastic puzzle glued to a piece of cardboard containing information about the puzzle. Most of their sixty or so different designs were based...

We show that the mixing time for the fifteen puzzle in an n× n torus is on the order of n logn.

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