Due to the disadvantages of human and equine rabies immunoglobulin, it is necessary to develop a substitute for HRIG and ERIG, especially for those people living in the developing countries. Because of higher affinity and lower immunogenicity of rabbit’s immunoglobulins, anti-rabies immunoglobulins specific to rabies virus were produced in rabbits as a bioreactor, and had been characterized by ...

Recent studies suggest that increased T-cell and autoantibody reactivity to lipids may be present in the autoimmune demyelinating disease multiple sclerosis. To perform large-scale multiplex analysis of antibody responses to lipids in multiple sclerosis, we developed microarrays composed of lipids present in the myelin sheath, including ganglioside, sulfatide, cerebroside, sphingomyelin and tot...

This document provides guidance to national regulatory authorities (NRAs) and vaccine manufacturers on the production and quality control of candidate live attenuated dengue virus vaccines by outlining the international regulatory expectations for product characterization. It should be read in conjunction with the WHO guidelines on nonclinical evaluation of vaccines (1), and the WHO guidelines ...

feat, it seemed reasonable to assume that accessibility and distribution of abortion services in Canada would increase because all independent health care facilities could now offer the procedure without criminal penalties. However, while decriminalization and regulation under the Health Act gave abortion the same status as other medical procedures, controversy over its existence and its delive...

A pneumothorax is defined as the presence of air between visceral and parietal pleura that leads to lung collapse. The term was used in the doctoral thesis of the French physician Itard in 1803, although the presence of an abnormal collection of air and fluid within the chest might have been inferred as early as the fifth century BC by physicians in ancient Greece who practiced the so-called Hi...