نتایج جستجو برای: 1371
تعداد نتایج: 1222 فیلتر نتایج به سال:
The structure of a protein depends critically on the complex interactions among its amino acid residues. It has long been hypothesized that interacting residues might tend to coevolve, but it is not known whether such coevolution is a general phenomenon across the proteome. Here, we describe a novel methodology called phylogeny-aided structural analysis, which uncovers robust signals of interac...
1 Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan 2 Stroke Centre, Aichi Medical University, Aichi 480-1195, Japan 3 Laboratory for Motor Neuron Disease, RIKEN Brain Science Institute, Wako, Saitama 351-0198, Japan 4 CREST, Japan Science and Technology Agency, 4-1-8, Honcho, Kawaguchi, Saitama 332-0012, Japan 5 Department of Neurology, Kyoto Univer...
Effective treatments for primary brain tumors and brain metastases represent a major unmet medical need. Targeting the CDK4/CDK6cyclin D1-Rb-p16/ink4a pathway using a potent CDK4 and CDK6 kinase inhibitor has potential for treating primary central nervous system tumors such as glioblastoma and some peripheral tumors with high incidence of brain metastases. We compared central nervous system exp...
Connu pour ses recherches sur la poesie persane et avoir fait connaitre le Dīwān de plus celebre poetesse iranienne, Jahān-Malik-Khātūn, Dominic Parviz Brookshaw s’interesse dans cet ouvrage a Ḥafiẓ (m. 1390) une perspective comparatiste. Il etudie les ghazals du poete Chiraz en prenant compte œuvres ceux qui lui etaient contemporains, tout particulierement Khwājū Kirmānī 1362 ou 1361), ‘Ubayd-...
Optical particle counter measurement of marine aerosol hygroscopic growth J. R. Snider and M. D. Petters University of Wyoming, Department of Atmospheric Science, Dept. 3038, 1000 East University Avenue, Laramie, WY 82071, USA Colorado State University, Department of Atmospheric Science, 1371 Campus Delivery, Fort Collins, CO 80523-1371, USA Received: 2 August 2007 – Accepted: 15 August 2007 – ...
www.sciencemag.org (this information is current as of September 11, 2009 ): The following resources related to this article are available online at http://www.sciencemag.org/cgi/content/full/325/5946/1371 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/325/5946/1371/DC1 can be ...
Objective: To examine a wide range of parentand teacher-reported behaviors in relation to child-reported depression and anxiety in preadolescence. Method: Subjects were participants in a longitudinal study of 420 preschool children from the general population that started in 1989. At second follow-up 8 years later (ages 10–11 years), usable parent information was obtained for 358 children. For ...
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