In autosomal dominant polycystic kidney disease (ADPKD), cyst inflation and continuous enlargement are associated with marked transepithelial ion and fluid secretion into the cyst lumen via cystic fibrosis transmembrane conductance regulator (CFTR). Indeed, the inhibition or degradation of CFTR prevents the fluid accumulation within cysts. The in vivomechanisms bywhich the lack of Polycystin-2 ...

www.sciencemag.org (this information is current as of January 5, 2009 ): The following resources related to this article are available online at http://www.sciencemag.org/cgi/content/full/317/5843/1366 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/317/5843/1366/DC1 can be fou...

[This corrects the article on p. 1366 in vol. 8, PMID: 28824694.].

The antagonistic effects of two new ƒÀ-receptors blocking agents, Ko 1313 and Ko 1366 against the chronotropic and inotropic responses to noradrenaline and tyramine were studied on the isolated right and left atria of guinea-pigs. From the KB values estimated by means of three different methods, it was found that the potencies of KO 1366 were 5 to 10 times and 5 to 7 times those of Ko 1313 in t...

PT.PLN (Persero) adalah Perusahaaan yang bertugas dalam menyalurkan energi listrik kepada masyarakat tampa adanya pemadaman. Reliability Index suatu metode untuk mengevaluasi parameter keandalan sistem distribusi tenaga memberikan kualiatas pelayanan pelanggan. Indeks digunakan mengukur SAIFI, SAIDI, dan CAIDI. Standar sebagai tolak ukur menentukan standar Keandalan IEEE Std 1366-2003 standart ...

Clark JP, Hudak PL, Hawker GA, et al. The moving target: a qualitative study of elderly patients’ decision-making regarding total joint replacement surgery. J Bone Joint Surg Am 2004;86–A:1366–74. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...

activity in vitro and in vivo. The several action mechanisms have been proposed to explain their in vivo anti-inflammatory activity. Many flavonoids exert anti-oxidative and free radical scavenging activities. Some derivatives modulate cellular activities of the inflammation-associated cells such as mast cells and lymphocytes. In particular, varieties of flavonoid derivatives including querceti...