We studied the effect in vitro of various concentrations of Triton WR-1339 on normolipidemic canine plasma and on the high density lipoproteins (HDL) isolated from this plasma by ultracentrifugation. As a preamble to this study, we established that Triton WR-1339 has a unimer molecular weight of 4,500, a micellar molecular weight of 180,000, and a critical micellar concentration (CMC) of 0.018 ...

PURPOSE We investigated the in vitro and in vivo anti-multiple myeloma activity of monoclonal antibody (mAb) 1339, a high-affinity fully humanized anti-interleukin 6 mAb (immunoglobulin G1), alone and in combination with conventional and novel anti-multiple myeloma agents, as well as its effect on bone turnover. EXPERIMENTAL DESIGN We examined the growth inhibitory effect of 1339 against mult...

, 1339 (2014); 343 Science et al. Chen Chen Electrocatalytic Surfaces Highly Crystalline Multimetallic Nanoframes with Three-Dimensional This copy is for your personal, non-commercial use only. clicking here. colleagues, clients, or customers by , you can order high-quality copies for your If you wish to distribute this article to others here. following the guidelines can be obtained by Permis...

1. The density-gradient distribution patterns of acid phosphatase, Trypan Blue and denatured (125)I-labelled albumin were studied by discontinuous sucrose- and isopycnic sucrose-density-gradient centrifugation on combined heavy and light mitochondrial (M+L) fractions of liver isolated from normal rats and from rats injected with Triton WR-1339. 2. The results obtained from the subfractionation ...

We developed a fast and simple method to detect presence or absence of DRC-1339 (CPTH: 3-Chloro-p-toluidine Hydrochloride) in birds that fed on DRC-1339 bait sites. We compared the effectiveness of the colorimetric method to the previously published analytical method using birds collected from DRC-1339 bait sites in Louisiana and Texas. We also conducted tests with caged red-winged blackbirds (...

Chrysin (5,7-dihydroxyflavone) is a flavonoid, natural component of traditional medicinal herbs, present in honey, propolis and many plant extracts. The objective of this study was to investigate the hypolipidemic properties of chrysin on Triton WR-1339-induced hyperlipidemia in female C57BL/6 mice. Triton WR-1339 was administered intraperitoneally (400 mg/kg) to overnight-fasted mice to develo...

Granulomatosis with polyangiitis (GPA) is a potentially lifethreatening ANCA-associated vasculitis (AAV) that typically involves the respiratory tract and the kidney. The introduction of glucocorticoid and CYC therapy in the 1960s dramatically improved the prognosis of affected patients, with 78% surviving at 5 years compared with a 1-year mortality in 80% of untreated patients [1]. No conventi...

The cholesterol lowering effect of SG-GN3, the extract of salted and fermented small shrimps, Acetes japonicus, was investigated in hypercholesterolemic animal models. Hypercholesterolemia was induced with Triton WR-1339 (nonionic detergent) or high cholesterol (HC)-diet. SG-GN3 significantly decreased total cholesterol (TC) in Triton WR-1339 model at 30 post-treatment hour (549.80 +/- 152.46 m...