Medulloblastoma (MB) is the most common malignant primary pediatric brain tumor and is currently divided into four subtypes based on different genomic alterations, gene expression profiles and response to treatment: WNT, Sonic Hedgehog (SHH), Group 3 and Group 4. This extensive heterogeneity has made it difficult to assess the functional relevance of genes to malignant progression. For example,...

Haemophilus parasuis causes contagious porcine Glässer’s disease leading to severe losses in the swine industry. In this study, we established an efficient Escherichia colibased system for the expression of H. parasuis major outer-membrane protein (MOMP) that has been known as a good vaccine candidate against Glässer’s disease. Use of an E. coli-derived pelB leader sequence made it possible to ...

This paper studies the effect of stator winding configuration on the performance of five-phase induction machines under healthy as well as faulty conditions. The study compares two connections, namely, star and pentagon connections. The comparison is conducted using both simulation and experimental results. The steady state model based on symmetrical components theory is introduced for both con...

Epidemiological studies have shown a positive association of colon cancer with hyperlipidemia. Furthermore, signaling generated by peroxisome proliferator-activated receptor (PPAR) alpha and gamma ligands, suggested to be candidate tumor preventive agents, has been shown to lower serum triglyceride levels. In the present study, we assessed hyperlipidemia in Apc-deficient mice, model animals for...

Carol V. Brown, Ph.D. Associate Professor Kelley School of Business Indiana University Bloomington, IN 47405-1309 (812) 855-2607 [email protected] Mohan V. Tatikonda, D.B.A. Associate Professor Kelley School of Business Indiana University Indianapolis, IN 46202-5151 (317) 274-2751 [email protected] Iris Vessey, Ph.D. Professor Kelley School of Business Indiana University Bloomington, IN 47405...

In 2010, Senate Bill 1309 included language to repeal an existing Arizona law that enables minors younger than 18 years of age to seek diagnosis and treatment of sexually transmitted diseases (STDs) without parental consent. Numerous implications were identified that would have stemmed from parental consent provisions originally proffered in Senate Bill 1309. These implications included diminis...

The phenotypic expression in familial adenomatous polyposis (FAP) is variable. This study compares the phenotype of 27 patients with an identical 5 base pair (bp) deletion at codon 1309 with a group of 61 matched patients with FAP where knowledge of specific mutations is not available and with seven other different mutations in 24 subjects. Patients with the codon 1309 deletion have significant...

Lead Authors (LA) Xuemei Bai (Australian National University) Thomas Buettner (United Nations Department of Economic and Social Affairs) Shobhakar Dhakal (Global Carbon Project and National Institute for Environmental Studies, Japan) David J. Fisk (Imperial College London, UK) Toshiaki Ichinose (National Institute for Environmental Studies, Japan) James E. Keirstead (Imperial College London, UK...

BACKGROUND The PulsePoint Respond app is a novel system that can be implemented in emergency dispatch centers to crowdsource basic life support (BLS) for patients with cardiac arrest and facilitate bystander cardiopulmonary resuscitation (CPR) and automated external defibrillator use while first responders are en route. OBJECTIVE The aim of this study was to conduct a North American survey to...