نتایج جستجو برای: 1277
تعداد نتایج: 486 فیلتر نتایج به سال:
The metabolism of delamanid (OPC-67683, Deltyba), a novel treatment of multidrug-resistant tuberculosis, was investigated in vitro using plasma and purified protein preparations from humans and animals. Delamanid was rapidly degraded by incubation in the plasma of all species tested at 37 C, with half-life values (hours) of 0.64 (human), 0.84 (dog), 0.87 (rabbit), 1.90 (mouse), and 3.54 (rat). ...
Irmgard Tegeder1,2,10, Michael Costigan1,10, Robert S Griffin1, Andrea Abele2, Inna Belfer3,4, Helmut Schmidt2, Corina Ehnert2, Jemiel Nejim4,9, Claudiu Marian2, Joachim Scholz1, Tianxia Wu4, Andrew Allchorne1, Luda Diatchenko5, Alexander M Binshtok1, David Goldman3, Jan Adolph2, Swetha Sama5, Steven J Atlas7, William A Carlezon8, Aram Parsegian8, Jörn Lötsch2, Roger B Fillingim6, William Maixn...
The struggle to delineate the relationship between theology and logic flourished in the thirteenth century and culminated in two condemnations in early 1277, one in Paris and the other in Oxford. To see how much and what kind of affect ecclessiastical actions such as condemnations and prohibitions to teach had on the development of logic in the Middle Ages, we investigate the events leading up ...
Introduction: Three-dimensional interactions between receptors and their ligands can modulate cell behavior. We have previously identified a region from type IV collagen, α1(IV)1263–1277, which promotes human melanoma cell adhesion and spreading in a conformationally-dependent manner [1]. These studies were expanded (a) using an alternative triple-helical construct and (b) incorporating a glyco...
Objective: To examine the specificity of methylphenidate effects on the processes that support the ability to rapidly and accurately coordinate the performance of multiple tasks in children with attention-deficit/hyperactivity disorder (ADHD). Method: Twenty children with ADHD performed the task-switching paradigm while on and off medication. The paradigm involves switching between two differen...
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