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Immune response (Ir) loci that map in the I region of the H-2 gene complex regulate the capacity to generate an immune response against numerous foreign antigens (1). Loci that map in the I region also control polymorphic~cell surface antigens that are expressed in immunocompetent cells (I-region-associated antigens or Ia loci) (2) and antigens that stimulate T cell proliferative responses betw...
Purpose: NF-kB transcription factor plays a key role in the pathogenesis of multiple myeloma in the context of the bone marrow microenvironment. Both canonical and noncanonical pathways contribute to total NF-kB activity. Recent studies have shown a critical role for the noncanonical pathway: selective inhibitors of the canonical pathway present a limited activity, mutations of the noncanonical...
http://www.sciencemag.org/cgi/content/full/319/5866/1086 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/1152993/DC1 can be found at: Supporting Online Material found at: can be related to this article A list of selected additional articles on the Science Web sites http://www.s...
Purpose: NF-kB transcription factor plays a key role in the pathogenesis of multiple myeloma in the context of the bone marrow microenvironment. Both canonical and noncanonical pathways contribute to total NF-kB activity. Recent studies have shown a critical role for the noncanonical pathway: selective inhibitors of the canonical pathway present a limited activity, mutations of the noncanonical...
PURPOSE NF-κB transcription factor plays a key role in the pathogenesis of multiple myeloma in the context of the bone marrow microenvironment. Both canonical and noncanonical pathways contribute to total NF-κB activity. Recent studies have shown a critical role for the noncanonical pathway: selective inhibitors of the canonical pathway present a limited activity, mutations of the noncanonical ...
Objective: To examine the link between childhood behavioral dimensions and adolescent conduct disorder (CD) among a large sample of boys and girls monitored longitudinally. Method: Teachers rated the behaviors of 1,569 children every year between kindergarten and grade 6. On the basis of these seven yearly ratings, groups of children who followed distinct trajectories on three behavioral dimens...
در این رساله ، حسامیزی ، یکی از عناصر تصویرساز در شعر صائب مورد بررسی و تحلیل قرار گرفته است. حسامیزی از دیرباز در شعر شاعران فارسی زبان به کار رفته است، اما کاربرد آن تا قبل از دوره سبک هندی چندان چشمگیر نیست. در سبک هندی بسیاری از شاعران از جمله بیدل و صائب حسامیزی را به طور گسترده در شعر خویش به کار برده اند.در فصل اول این رساله مباحث نظری حسامیزی عنوان شده است که شامل: تعریف حسامیزی ، حسامی...
A diode-pumped Nd:LuVO4 laser emitted at 1086 nm in σ polarization has been demonstrated. A power of 2.37 W at 1086 nm has been achieved in continuous-wave (cw) operation with a fiber-coupled laser diode emitting 18.2 W at 809 nm. Moreover, intracavity second-harmonic generation in cw mode has also been demonstrated with a power of 528 mW at 543 nm by using a LiB3O5 (LBO) nonlinear crystal.
www.sciencemag.org (this information is current as of March 19, 2008 ): The following resources related to this article are available online at http://www.sciencemag.org/cgi/content/full/319/5866/1086 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/1152993/DC1 can be found at: ...
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