introduction: the use of low energy isotopes such as  103 pd in brachytherapy for the treatment of cancers  such as prostate, eye, head, neck, breast and cervix is increasing. in this regard, different models of pd- 103  seeds  have  been  designed  and  manufactured  at  the  agricultural,  medical  and  industrial  research  school (amirs) of atomic energy organization of iran. in this resear...

PURPOSE Standard brachytherapy sources emit radiation in a non-preferential direction away from the source. Though treatment outcomes are good, this can lead to late skin and subcutaneous toxicities in sensitive structures. Proposed low dose rate directional sources for interstitial brachytherapy, showed to have an improvement in the dose uniformity within the subcutaneous volume, reduction in ...

Introduction: The use of low energy isotopes such as  103 Pd in brachytherapy for the treatment of cancers  such as prostate, eye, head, neck, breast and cervix is increasing. In this regard, different models of Pd- 103  seeds  have  been  designed  and  manufactured  at  the  Agricultural,  Medical  and  Industrial  Research  School (AMIRS) of Atomic Energy Organization of Iran. In this resear...

Brachytherapy to treat prostate cancer uses transrectal ultrasound to guide transperitoneal needle implantation of titanium-shelled radioactive seeds. The standard external dimensions of all seeds used for prostate brachytherapy is 4.5 mm in length and 0.85 mm in diameter. Gland deformation and needle deflection during implantation allow seed-placement errors that cause suboptimal dosimetry. Co...

MicroRNAs play extensive roles in cellular development. Analysis of the microRNA expression pattern during intestinal cell proliferation in early life is likely to unravel molecular mechanisms behind intestinal development and have implications for therapeutic intervention. In this study, we isolated mouse intestinal crypt cells, examined the differences in microRNA expression upon IGF-1 stimul...

An equation is derived for the TG43 geometry function, G(r,theta), of a linear brachytherapy source in terms of its active length. This equation is validated by comparison to published values. It is then used to calculate values of the geometry function for the Model 200 (103)Pd seed, which is a segmented linear source.

BACKGROUND Prostate cancer is the most common cancer diagnosed in men. An increasing number of these patients are seeking minimally invasive procedures such as transperineal interstitial permanent radioactive seed prostate brachytherapy. METHODS This paper reviews the historical perspective and the current advances in transperineal interstitial permanent radioactive seed prostate brachytherap...