the aim followed in the present study was to evaluate the effect of estradiol (e2) injection and injection (either intramuscular (i.m) or intravenous (i.v)) of various doses of oxytocin (ot) on cervix dilation and on conception rate in zandi ewes during late breeding season. sixty three ewes were randomly selected. in experiment 1, the ewes received 100 µl e2 and 12h later were divided and assi...

the aim of this study was to evaluate the effect of estradiol (e2), oxytocin (ot), relaxin (relaximol) injection and prostaglandin e1 (misoprostol) suppository on the cervix dilation, time of cervical dilation persistency and pregnancy rate of zandi ewes using artificial insemination. eighty 3-4 years old and 55±2.5 kg weight ewes were used for this study. in experiment 1, the ewes were assigne...

Fragile X syndrome (FXS) is a rare inherited genetic disorder causing severe intellectual disability and autistic-like symptoms. Individuals with FXS, males in particular, often exhibit extreme eye gaze avoidance and hyperarousal when they encounter stressful social situations. We investigated whether oxytocin (OT), a hormone with prosocial and anxiolytic effects, could alleviate symptoms of so...

Oxytocin (OT) is a neuropeptide that mediates a variety of complex social behaviors in animals and humans. Intranasal OT has been used as an experimental therapeutic for human conditions characterized by deficits in social functioning, especially autism spectrum disorder and schizophrenia. However, it is currently under intense debate whether intranasal delivery of OT reaches the central nervou...

Abstract Introduction Oxytocin (OT), a peptide hormone, is known to be involved in social interaction and the pleasure we derive from it produced posterior pituitary. This neurotransmitter has potential role love, female reproductive functions, bonding. OT released by both males females, during skin contact sexual arousal orgasm/ejaculation (1,2). effects on brain are dependent its interactions...

We determined the effects of oxytocin (OT) and prostaglandin F2α analogue (PG) added to extended boar semen on duration artificial insemination (AI) reproductive performance pigs bred in July August (temperate climate Central Europe). Eighty gilts second parity sows (G+SP) sixty-four multiparous (M) were divided into three groups. Group OT (11 G+SP 37 M) group PG (20 28 artificially inseminated...

BACKGROUND Central oxytocin (OT) is critically involved in mediating social bonding and protecting against stress, depression, and anxiety. In animal models, early social experiences induce changes in central OT systems. In humans, early parental separation (EPS) increases the risk for emotional disorders in adulthood. We examined neuroendocrine responses to intranasal OT administration in men ...

Human beings routinely help strangers at costs to themselves. Sometimes the help offered is generous-offering more than the other expects. The proximate mechanisms supporting generosity are not well-understood, but several lines of research suggest a role for empathy. In this study, participants were infused with 40 IU oxytocin (OT) or placebo and engaged in a blinded, one-shot decision on how ...

The aim of the present study was to investigate the effect of systemic oxytocin (OT) and vasopressin (VP) on the motility of stomach and duodenum. Two plastic balloons made of condom were inserted into stomach and duodenum to monitor the change of mean pressure. Intravenous injection of OT (0.1-0.8 microg kg(-1)) or VP (0.02-0.08 IU kg(-1)) dose-dependently increased the stomach and duodenum pr...