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Background: Resveratrol (RSV) provides several important biological functions in wide variety of cells. In this study, we investigated the molecular mechanisms underlying anti-inflammatory effect of RSV on HepG2 cells by assessing the gene expression of RelA and c-Jun- subunits of NF-κB and AP-1 transcription factors. Methods: HepG2 cells were settled in a serum- free medium...
Jun–08 ........................... 21 6,962,199,302,412 331,533,300,115 0.135 .............................. ........................................ Jul–08 ............................. 22 8,104,256,787,805 368,375,308,537 0.105 .............................. ........................................ Aug–08 ........................... 21 6,106,057,711,009 290,764,652,905 ¥0.237 ...................
IL-10 is a key regulatory cytokine produced by T lymphocytes. Although Th2 cells are a major source of IL-10, little is known about IL-10 gene regulation in Th2 cells. High levels of IL-10 mRNA transcription are induced in the Th2 clone D10 after PMA plus ionomycin (P/I) stimulation; however we found that the IL-10 promoter was not inducible by P/I in D10 cells. We therefore sought regulatory r...
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