background and aims: glycoprotein b (gb) is among the most important immunogenic proteins of hsv-1 that is now being used as recombinant vaccine to induce protectively against the virus. it is believed that gb is responsible for induction of neutralizing antibody and up to 90% of ctl (cytotoxic t cell) activity against hsv-1 in some haplotypes. methods: in the present study the antibody titer i...

introduction: glycoprotein b (gb) is the major antigen for induction of humoral responses against human cytomegalovirus (hcmv) making it an attractive candidate for immune prophylaxis. in the present study, the humoral immune response of balb/c mice to a truncated hcmv gb protein fused with gfp was evaluated. methods: the truncated gb coding sequence was synthesized and cloned in pegfpn1 eukary...

The nine-banded armadillo (Dasypus novemcinctus mexicanus Peters) was chosen for this study so that a comparison could be made of the salivary mucus glycoproteins of an ancient mammalian species with those derived from previously studied, more highly evolved species. Two mucus glycoproteins, armadillo submandibular glycoprotein A and armadillo submandibular glycoprotein B, were prepared from th...

purpose: the aim of the present study was to detect the expression of p-glycoprotein (p-gp) and multi-drug resistance associated protein 1 (mrp1) in retinoblastoma tumors, and analyze the relationship between its expression, the clinico-pathological features and recurrence. methods: p-gp and mrp1 expression in formalin-fixed paraffin-embedded retinoblastoma bearing ocular tissue sections from 2...

The present study explores the efficacy of plant-derived natural products (PDNPs) against spike glycoproteins (S-glycoprotein) SARS-CoV-2 variants using molecular docking, ADMET, dynamics (MD) simulation and density-functional theory (DFT) analysis. In all, 100 PDNPs were screened glycoprotein variants, namely alpha (B.1.1.17), beta (B.1.351), delta (B.1.617), gamma (P.1) omicron (B.1.1.529). R...