This study investigated the anticonvulsant activity of a new phthalazine tetrazole derivative, QUAN-0808 (6-(4-chlorophenoxy)-tetrazolo[5,1-a]phthalazine), in the mouse maximal electroshock (MES) seizure model. The neurotoxicity of QUAN-0808 was investigated using the rotarod neurotoxicity test in mice. QUAN-0808 exhibited higher activity (median effective dose, ED(50) = 6.8 mg/kg) and lower ne...

BACKGROUND QUAN-0808 (6-(4-chlorophenoxy)-tetrazolo[5,1-a]phthalazine), a new phthalazine tetrazole derivative, was evaluated for the anti-inflammatory and analgesic effects. METHODS Xylene-induced ear edema, carrageenan (Carr)-induced paw edema, and acetic acid-induced capillary permeability hyperactivity in mice were used to assess the anti-inflammatory effect; acetic acid-induced writhing ...

1Program for Clinical Research, Department of Dermatology, University of California San Francisco, CA 94143 0808, USA; 2UC Berkeley-UC San Francisco Joint Medical Program, University of California, Berkeley, CA, USA; 3Physician Moms Group; 4Department of Otolaryngology Head and Neck Surgery, Stanford Medicine, CA, USA; 5Center for Policy and Research in Emergency Medicine, Department of Emergen...

*Corresponding author: Aru Narayanasamy, Associate Professor, National Teaching Fellow, Academic Associate (HEA), Fellow of Higher Education Academy, Member of BACP Coaching Division, University of Nottingham, Faculty of Medicine & Health Science, School of Health Sciences, Room 51, C Floor, Queens Medical Centre, Nottingham NG7 2HA, United Kingdom, Tel: +44 (0)115 823 0808; E-mailAru.Narayanas...

1 University of Illinois at Urbana-Champaign, 1205 W. Clark St. Urbana, IL 61801, USA 2 HLRS, University of Stuttgart, D-70550 Stuttgart, Germany 3 HPCE, NEC Deutschland GmbH, Hansaallee 101, 40549 Düsseldorf, Germany 4 Lawrence Livermore National Laboratory, Box 808, L-557, Livermore, CA 94551-0808 5 Mathematics and Computer Science Division, Argonne National Laboratory, 9700 S. Cass Avenue, A...

Shiba Palace Clinic, 6th Floor, Daiwa A Hamamatsu-cho Building, 1-9-10, Hamamatsu-Cho, Minato-Ku, Tokyo, 105-0013, Japan; Laboratory of Dermatological Physiology, Faculty of Pharmaceutical Sciences, Josai University, Keyakidai, Sakado-Shi, Saitama Prefecture, 3500295, Japan; Okayasu Shoten Co., Ltd., 17-16 Akayama-Honcho, Koshigaya-Shi, Saitama Prefecture, 343-0808, Japan; SOUKEN Co., Ltd., 3 F...

1 University of Illinois at Urbana-Champaign, 1205 W. Clark St. Urbana, IL 61801, USA 2 HLRS, University of Stuttgart, D-70550 Stuttgart, Germany 3 HPCE, NEC Deutschland GmbH, Hansaallee 101, 40549 Düsseldorf, Germany 4 Lawrence Livermore National Laboratory, Box 808, L-557, Livermore, CA 94551-0808 5 Mathematics and Computer Science Division, Argonne National Laboratory, 9700 S. Cass Avenue, A...

This study deals with innovative idea of touchpad controlled vehicle. Normally in such system touchpad is interfaced with ADC [0808/MCP 3208] which gives the co-ordinates of the points touch by the user on touchpad. But in this study Programmable Intercombination Circuit (PIC) [18F4550/18C4550] is used purposefully instead of ADC as input signal were in analog which required converting into dig...