نتایج جستجو برای: 0632 and 056
تعداد نتایج: 16827472 فیلتر نتایج به سال:
Understanding the molecular basis of ligand binding to receptors provides insights useful for rational drug design. This work describes development of a new antagonist radioligand of the type 1 cholecystokinin receptor (CCK1R), (2-fluorophenyl)-2,3-dihydro-3-[(3-isoquinolinylcarbonyl)amino]-6-methoxy-2-oxo-l-H-indole-3-propanoate (T-0632), and exploration of the molecular basis of its binding. ...
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In searching for opportunities to exploit the benefits of silicon in TRPV1 research, we tried to investigate the pharmacological effects of sila-substitution (C/Si exchange) of tert-butyl group in the MK-056 series. Compound 13a, with a 4-positioned trimethylsilanyl group on the B ring in place of tert-butyl group, exhibited the most potent antagonist activity with IC(50) values of 0.15 microM,...
*Corresponding Author: Dr. Srinivas. C, Department of Microbiology and Biotechnology, Bangalore University, Jnanabharathi Campus, Bangalore-560 056, Karnataka, India. Page| 342 Efficacy of Trichoderma asperellum against Ralstonia solanacearum under greenhouse conditions Narasimha Murthy K, Nirmala Devi D and Srinivas C* Department of Microbiology and Biotechnology, Bangalore University, Jnanabh...
S. M. Oliveira Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Campo Mártires da Pátria, 130, 1169-056 Lisbon, Portugal and MedicalConsult, SA, Campo Grande, 56-88A, 1700-093 Lisbon, Portugal N. J. Teixeira Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Campo Mártires da Pátria, 130, 1169-056 Lisbon, Portugal and Escola Superior de Tecnologia da Saúde de Lisboa, Institu...
First evidence for a Vibrio strain pathogenic to Mytilus edulis altering hemocyte immune capacities.
Bacterial isolates were obtained from mortality events affecting Mytilus edulis and reported by professionals in 2010-2013 or from mussel microflora. Experimental infections allowed the selection of two isolates affiliated to Vibrio splendidus/Vibrio hemicentroti type strains: a virulent 10/068 1T1 (76.6% and 90% mortalities in 24 h and 96 h) and an innocuous 12/056 M24T1 (0% and 23.3% in 24 h ...
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