The chromatography fractionation of the hexane, chloroform and ethyl acetate extracts from the leaves and stems of Rourea doniana Baker, Connaraceae, resulted in the isolation of five triterpenes (lupeol, lupenone, α-amyrenone, β-amyrenone, and taraxerol), a flavonol (7,4’-dimethylkaempferol), a coumarin (scopoletin) and four phytosteroids (β-sitosterol, stigmasterol, β-sitosteryl-3-Oβ-D-glucop...

Vitex leucoxylon is known to possess anti inflammatory activity. It was accidentally observed that local people of some regions use the leaves of vitex leucoxylon in jaundice and other liver ailments. There was no report of pharma-cological screening on liver. Hepatoprotective activity of the alcoholic extract of the leaves of vitex leucoxylon was found to be effective in protecting the liver f...

INTRODUCTION Increased bleeding is the most common cause of intrauterine device (IUD) removal. The use of alternative therapies to treat bleeding has increased due to the complications of medications. But most alternative therapies are not accepted by women. Therefore, conducting studies to find the right treatment with fewer complications and being acceptable is necessary. This study aimed to ...

This study was done to assess the total phenolic compounds (TPC) and 1, 1-diphenyl-2picrylhydrazyl (DPPH) scavenging activity in the flowers and leaves of Clitoria ternatea and Vitex negundo Linn. by using methanol and water extraction. TPC were evaluated using Folin-Ciocalteau method. Methanol was more efficient in extracting phenolic compounds compared with water in measuring TPC. Vitex negun...

The in vitro antioxidant potential assay between ethanolic extracts of two species from the genus Vitex (Vitex negundo L. and Vitex trifolia L.) belonging to the Lamiaceae family were evaluated. The antioxidant properties of different extracts prepared from both plant species were evaluated by different methods. DPPH scavenging, nitric oxide scavenging, and β-carotene-linoleic acid and ferrous ...

In present study the effects of anti-inflammatory and antinociceptive of vitex hydro-alcoholic extract were evaluated on male mice. In inflammatory test mice were divided into 7 groups: first group was control. The second group, positive control group, received dexamethasone (15 mg/kg) and the other five groups received different doses of hydroalcohol extract of Vitex fruit (265, 365, 465, 565,...

A multicentric noninterventional trial (open study without control) to investigate the efficacy and tolerance of a drug in a large number of patients under routine medical conditions was performed for a new solid preparation from an extract of the fruit of Vitex agnus castus (VAC, Vitex, chaste tree, Chasteberry) in 1634 patients suffering from premenstrual syndrome (PMS). A specific questionna...

Plants and their active constituents play an important role in the prevention of a variety of ailments. Most of the species of the Genus Vitex are used therapeutically in ancient Indian systems of medicine especially, Ayurveda and Siddha. The genus Vitex contains about 270 species distributed around the world. These species contain a variety of potentially bioactive molecules, such as iridoids,...