In this study, a bioadhesive dosage form of clotrimazole was designed using a combination of bioadhesive polymers Carbopol 934P, sodium carboxymethyl cellulose and sodium alginate in different ratios. The bioadhesive strength was evaluated by measuring the force required to detach the tablets from porcine vaginal mucosal membrane. The strong interaction between polymer and mucus lining of the t...

Most commonly used conventional dosage forms are tablets and capsules. Compressed tablets are the most widely used dosage forms due to its numerous advantages. They are convenient, easy to administer, economic, tamper-proof, easy to packing and transport and more stable than other oral dosage forms [1]. Also tablets have certain special release profile products such as enteric or delayed releas...

The Gram's stain technique was never intended for use as a diagnostic tool. This technique does not possess the characteristics necessary to yield such specific results. However, there is.no doubt that the Gram's stain is a useful technique to distinguish the morphology of bacteria. It is also of significant use, to a degree, in distinguishing two major groups of bacteria, the gram-positive and...

background rational prescription is a considerable issue which must be paid more attention to assess the behavior of prescribers. the aim of this study was to examine factors affecting family physicians’ drug prescribing.   methods we carried out a retrospective cross-sectional study in khuzestan province, iran in 2011. nine hundred eighty-six prescriptions of 421 family physicians (including 3...

The purpose of this work was to develop and characterize a novel delivery system of post-expansile hydrogel foam aerosol of propylene glycol-embodying liposomes (PG-liposomes) (PEHFL) for vaginal drug delivery applications. Matrine (MT) was used as a model drug to investigate the vaginal mucous membrane permeation behavior of MT from PEHFL versus PG-liposomes foam aerosol (PLFA), hydrogel foam ...

A simple and sensitive high performance liquid chromatographic method with electrochemical detection is described for the quantitative determination of the amoxycillin and clavulanic acid in pharmaceutical dosage forms. Separation of sample components occurs on a reversed phase C18 column with a mobile phase consisting of methanol-water-phosphate buffer. For the amperometric detection, the pote...

The pharmacist, both in community and hospital pharmacy practice, is often challenged with the preparation of a liquid dosage form not available commercially for paediatric patients, those adults unable to swallow tablets or capsules and patients who must receive medications via nasogastric or gastrostomy tubes. Recognising the lack of information available to healthcare professionals, a genera...

Background Rational prescription is a considerable issue which must be paid more attention to assess the behavior of prescribers. The aim of this study was to examine factors affecting family physicians’ drug prescribing.   Methods We carried out a retrospective cross-sectional study in Khuzestan province, Iran in 2011. Nine hundred eighty-six prescriptions of 421 family physicians (including 3...