BACKGROUND Azithromycin is recommended for the treatment of uncomplicated urogenital chlamydia infection although the standard 1gram dose sometimes fails to eradicate the infection (treatment failure). One hypothesis proposed for treatment failure has been insufficient levels of the antibiotic at the site of infection. We developed an assay using liquid chromatography and tandem mass spectromet...

We investigated the protective role of antibodies in vaginal secretions of mice that were immune to vaginal challenge with herpes simplex virus type 2 (HSV-2). Unfractionated vaginal immunoglobulins from immune and nonimmune mice and affinity-purified immunoglobulin G (IgG) and secretory IgA (S-IgA) from immune secretions were adjusted to their concentrations in vivo. Wild-type HSV-2 was incuba...

BACKGROUND Bacterial vaginosis (BV) is one of the most common urogenital infections among women of reproductive age that represents shifts in microbiota from Lactobacillus spp. to diverse anaerobes. The aim of our study was to evalute the diagnostic values of Gardnerella, Atopobium, Eggerthella, Megasphaera typeI, Leptotrichia/Sneathia and Prevotella, defined as a vaginal pathogenic community f...

conclusions evaluation of iranian traditional dosage forms like vaginal and rectal types could be an attractive topic of research and the current study can briefly represent the iranian traditional pharmaceutical knowledge on vaginal and rectal drug delivery. objectives the aim of this study is the investigation about iranian traditional pharmaceutical dosage forms of vaginal and rectal medicat...

OBJECTIVE Vaginal apex pain is a subset of chronic pelvic pain commonly treated with surgical excision of the vaginal apex. Our objective was to estimate long-term postoperative pain levels, recovery time, and return to sexual function in women who have undergone vaginal apex repair for chronic vaginal apex pain. METHODS Since 1995, 45 women have undergone vaginal apex repair at our instituti...

background: group b streptococcus (gbs) colonizes the gastrointestinal and genitourinary tract of 10-40% of pregnant women and it is a major cause of neonatal morbidity and mortality. objective: this study was to evaluate whether vaginal gbs culture results alter after digital vaginal examination or not. antibiotic resistance pattern of this specie has been also assessed. materials and methods:...

conclusions higher ods score in females who had c/s showed that c/s could not protect the pelvic organ from pregnancy and delivery trauma. it seems that episiotomy has a protective effect during vd; it can reduce the severity of trauma in pelvic organs during childbearing. results in 30 consecutive females undergoing starr for the treatment of ods, who enrolled in this prospective study, 19 (63...

introduction foreign body insertion is a common and important cause of pre-pubertal vaginal bleeding. case presentation we present a three-year-old girl who referred to our clinic with abnormal vaginal bleeding without any other symptoms. the primary assessment revealed a radio-opaque round solid mass in the pelvic cavity. following vaginoscopy, the button battery was finally removed under gene...

conclusions the clinicians should always think of foreign bodies in the vagina in cases of chronic, antibiotic resistant vaginal discharge and lower abdominal pain especially in young girls. introduction foreign body in the vagina is a common cause of vaginal discharge, which may be either purulent or hemorrhagic. case presentation this problem may produce symptoms or be asymptomatic for long p...