ABSTRACTPropionibacterium acnes is propounded as one of the significant factors in occurrence of acne. Today, due to development of the antibiotic resistance, most of the acne treatments are faced with failure. In order to determine the antibiotic resistance of the P.acnes strains isolated from the patients with acne, this research has been carried out. 70 samples collected using microbial cult...

Antibiotic resistance is a heterogeneous phenomenon. It does not only differ between countries or states, but also between wards of hospitals, where different resistance patterns have been found. To support clinicians in administering empiric antibiotic therapy, we developed software to present information about antibiotic resistance using a mobile concept. A pre-existing infrastructure was dep...

BACKGROUND Appropriate antibiotic treatment decreases mortality, while superfluous treatment is associated with antibiotic resistance. We built a computerized decision support system for antibiotic treatment (TREAT) targeting these outcomes. METHODS Prospective cohort study comparing TREAT's advice to physician's treatment followed by a cluster randomized trial comparing wards using TREAT (in...

conclusions antibiotic resistance gene cassettes may be carried on integron or other genetic elements. the purpose of this study was to detect integron or genomic islands involved in antibiotic resistance profile of the isolates of h. influenzae collected in this study. results of the twenty isolates, all (100%) were resistant to clindamycin, chloramphenicol and tetracycline, 95% to amoxicillin...

abstractpropionibacterium acnes is propounded as one of the significant factors in occurrence of acne. today, due to development of the antibiotic resistance, most of the acne treatments are faced with failure. in order to determine the antibiotic resistance of the p.acnes strains isolated from the patients with acne, this research has been carried out. 70 samples collected using microbial cult...

This prospective, randomized, and controlled study examined the effects of tumor necrosis factor soluble receptor type I (sTNFRI, a TNF-α antagonist) on experimentally induced rhinosinusitis in rats. The experimental groups received an instillation of lipopolysaccharide (LPS) plus an intramuscular injection of amoxicillin/clavulanate (antibiotic group), an instillation of sTNFRI (sTNFRI group),...

sepsis constitutes an important cause of hospital admission with a high mortality rate. appropriate antibiotic therapy is the cornerstone of therapy in patients with sepsis. although numerous studies have recommended early antibiotic initiation in severe sepsis or septic shock stages of sepsis syndrome, its role in treatment of patients with sepsis who have not entered these stages remains to b...

background: human exposure to antibiotic resistant bacteria (arb) is a public health concern which could occur in a number of ways. wastewaters seem to play an important role in the dissemination of bacteria and antibiotic resistant genes (args) in our environment. the aim of this study was to evaluate the occurrence of three groups of arb and their resistance genes in hospital and municipal wa...