Motivation Recent high-throughput sequencing advances have expanded the breadth of available omics datasets and the integrated analysis of multiple datasets obtained on the same samples has allowed to gain important insights in a wide range of applications. However, the integration of various sources of information remains a challenge for systems biology since produced datasets are often of het...

Background Immune checkpoint inhibitor (ICI) therapy has greatly improved the prognosis of advanced cancers but is often complicated by immune-related adverse events (irAEs). Biomarkers ICI safety and efficacy are needed. Objectives To identify autoantibodies (AAbs) associated with irAEs cancer outcomes in ICI-treated patients. Methods This analysis used clinical data biospecimens from a prospe...

Introduction: Conventionally, Arterial Spin Labeling (ASL) is utilized to measure perfusion. The shortest echo time possible is typically used to achieve the best signal-to-noise ratio (SNR). Recently, these perfusion experiments were extended to include T2 measurements of the difference signal [13], where the acquisition of data at different TEs is needed to sample the signal decay. This is a ...

The behaviors displayed and statements articulated during supervision are a function of the supervisee’s current stage of development (Loganbill, Hardy, & Delworth, 1982). The various forms of supervisee resistance often result when the supervisory style does not match the supervisee’s readiness level or developmental stage (Rando, 2001). By integrating the use of the Loganbill et al. Developme...

Every day thousands of surgical procedures are performed to replace or repair tissue that has been damaged through disease or trauma. The developing field of tissue engineering (TE) aims to regenerate damaged tissues by combining cells from the body with highly porous scaffold biomaterials, which act as templates for tissue regeneration, to guide the growth of new tissue. This article describes...

I t is a gender read ing of F lorence N ight ingale 's ma in work, "Notes on N u rs ing : what is and what isn 't" , a book which brings together the pr inc ip les and essential e lements of modern n u rs ing , professional ized i n England i n the second ha lf of the X IX centu ry and the way the profession was constituted i n Brazi l , as expl icited i n the work of Glete de Alcantara : "Mode...

s of Invited and Contributed Presentations 1.0 Novel Aspects of the Endothelin System....................................................................13 2.0 The Immune System and Endothelin......................................................................13 3.0 Submitted Abstracts..........................................................................................13 4.0 ET, Sex and ...