As has been shown by Traugott & Dasher (2002), discourse markers proceed along the following grammaticalization cline; non-subjective > subjective > intersubjective uses. We look for evidence of this grammaticalization cline using a previously unexamined discourse marker in Spanish no sé (‘I don’t know’). Inline with Bybee & Sheibman (1999), we show that no sé seems to be stored in lexical repr...

Background and Aims: Immunohistochemical tests are one of the most important tests, which are under study to determine the prognosis of the cancers such as transitional cell carcinoma. By the time, flexible cystoscopy and urine cytology are the routine tests for following up the patients with transitional cell carcinoma, which are both operator dependent. On the other hand, cystoscopy is an inv...

We studied 52 patients, each with a lumbosacral transitional vertebra. Using MRI we found that the lumbar discs immediately above the transitional vertebra were significantly more degenerative and those between the transitional vertebrae and the sacrum were significantly less degenerative compared with discs at other levels. We also performed an anatomical study using 70 cadavers. We found that...

Transitional immature B cells undergo apoptosis and fail to proliferate in response to BCR cross-linking, thus representing a target for negative selection of potentially autoreactive B cells in vivo. In agreement with recent reports, transitional B cells were divided into developmentally contiguous subsets based on their surface expression of CD23. When transferred, CD23(+) transitional B cell...

OBJECTIVE To investigate whether transitional incidents can be identified from the medical records of the general practitioners and the hospital and to assess the concordance of transitional incidents between medical records and patient interviews. DESIGN A pilot study. SETTING The study was conducted in 2 regions in the Netherlands: a rural and an urban region. PARTICIPANTS A purposeful ...