The antifungal activity of extracts of Tinospora cordifolia (leaves), Moringa oleifera (bark) and Trachyspermum ammi (seeds) at three concentrations viz., 25, 50, 75% (v/v) were evaluated in vitro by poisoned food technique against Fusarium oxysporum f. sp. lycopersici and Fusarium solani causing wilt disease on tomato and brinjal plants. The antifungal activity was assessed in terms of percent...

Tinospora cordifolia (Willd.), belonging to the family Menispermaceae, is known to exhibit a wide array of pharmacological properties such as antiulcer, anti-inflammatory and antiarthritic properties. In the present study an attempt has been made to evaluate the antioxidant and glucose uptake potential of T. cordifolia leaves extract in vitro. Phytochemical analysis of the leaves extract reveal...

Ethanol extracts of Ocimum sanctum Linn. and Tinospora cordifolia (Willd.) Miers ex Hook. f. & Thoms. were included for the present in vitro study. Pepsin was used as a substitute for HIV-protease to evaluate inhibitory activity of these extracts, as pepsin has close resemblance with HIV-protease in proteolytic activity. Extracts of O. sanctum and T. cordifolia showed potent inhibitory activity...

Dietary excess of lipids causes substantial health disorders like hyperlipemia, obesity and cardiovascular problems. Use of lipase and α-glucosidase inhibitors in combination is considered to be the ideal therapy for obesity control. Anti-obesity activity of natural products is usually assessed by inhibition of pancreatic lipase activity by the preparations. We have reported earlier that some k...

BACKGROUND & OBJECTIVE The effect of aqueous extract of Tinospora cordifolia, an immunomodulator with antimalarial activity along with chloroquine was studied in the treatment of three cases of hyper-reactive malarious splenomegaly in District Hospital, Daltonganj town, Jharkhand, India. These cases were partial/slow responders to the conventional antimalarial drug chloroquine. METHODS Aqueou...

Thirty two apparently healthy local non descript cows were experimentally divided into two groups viz. treatment and control group having 16 animals each. The animals under treatment group were fed dried stem powder of Tinospora cordifolia (100 mg/ kg BW) by mixing it in concentrate mixture for a period of 5 days. The control group animals were fed equal amount of the basal concentrate mixture ...

OBJECTIVE To optimize the conditions for the extraction of alkaloid palmatine from Tinospora cordifolia by using response surface methodology (RSM) and study its anticancerous property against 7,12-dimethylbenz(a)anthracene (DMBA) induced skin carcinogenesis in Swiss albino mice. METHODS The effect of three independent variables, namely, extraction temperature, time, and cycles was investigat...

Pharmaceutical Manufacturing is an important enterprise and oral tablet manufacturing is the most significant of all, because more drugs are made as tablets than any other dosage form. The way of tablet manufacturing has been undergoing change in recent years and is likely to head in new directions. In this study Tinospora cordifolia (guduchi) a freely available, a climbing shrub belonging to t...

Plants are the sources of many bioactive compounds containing many primary metabolites like, carbohydrates (starch, sugar), proteins, phenols, ascorbic acid etc. are useful for flavoring, fragrances, insecticides, sweeteners and natural dyes (Kaufman). During the present research work, root, stem, leaf and calli of the plant were evaluated quantitatively for the analysis of chlorophyll, sugars,...

The present study was carried out to investigate the antidyslipidemic activity of Tinospora cordifolia stem extract in alloxan-induced (150 mg/kg body wt.) diabetic rats. There was significant increase in plasma markers of diabeticdyslipidemia namely: the levels of glucose, glycosylated hemoglobin(HbA1c) lipid peroxide, total lipid and free fatty acids (FFA).The abnormalities with lipid metabol...