AIM The aim of this study was to investigate whether the Indian Diabetes Risk Score (IDRS) could assist in classifying type 2 diabetes mellitus (T2DM) and non-T2DM among patients attending clinics in India. METHODS Patient records from 2006 through 2009 were taken from the clinical database of a tertiary care diabetes hospital in Chennai, Southern India. A total of 8747 patients with diabetes...

Accumulated evidence indicates that microRNA (miRNA or miR) is involved in the development of type 2 diabetes (T2DM). Several studies have shown that single nucleotide polymorphisms (SNPs) located in miRNAs are associated with T2DM in Caucasian populations. The association studies of miRNA's SNPs with T2DM in Asian are rarely reported, and there are distinct genetic differences between Caucasia...

BACKGROUND Coffee consumption has been shown to be inversely associated to type 2 diabetes mellitus (T2DM), but evidence in Chinese populations is limited. We investigated the relationship between coffee consumption and T2DM in a population-based cohort of middle-aged Chinese. MATERIALS AND METHODS We studied 2332 subjects who participated in the Taichung Community Health Study in Taiwan in 2...

considering that mapk (mitogen- activated protein kinase) signaling pathway has an important role in the progression of inflammatory cytokine secretion in type 2 diabetes mellitus (t2dm), we have recently investigated the reported genetic polymorphism from genome wide association study in map3k1 (mitogen-activated protein kinase kinase kinase 1) in diabetes as an important member of mapk signal...

conclusions camel milk increased insulin level in patients with t2dm and might contribute to glycemic control in t2dm. results mean of insulin concentration was significantly increased from 64.59 to 84.03 pmol/l in the camel milk group during the study (p < 0.05). no significant differences were shown in fasting blood sugar, lipid profile, and blood pressure between the two groups at the end of...

Background: This study estimated the prevalence, recurrence, and predisposing factors of self-reported urinary tract infections (UTIs) and genital infections among adults with and without type 2 diabetes mellitus (T2DM). Methods: In the US Study to Help Improve Early evaluation and management of risk factors Leading to Diabetes (SHIELD) 2008 survey, respondents reported how many times in the pa...

Objective: People with type 2 diabetes (T2DM) have impaired exercise responses even in the absence of cardiovascular complications. One key factor associated with the exercise intolerance is abnormally slowed oxygen uptake ( O2) kinetics during submaximal exercise. The mechanisms of this delayed adaptation during exercise are unclear but likely relate to impairments in skeletal muscle blood flo...

Background: Existence of myocardial insulin resistance (IR) has been reported in type II diabetics (T2DM) and coronary artery disease (CAD). Improvement in heart and skeletal muscle IR after thiazolidinedione’s therapy was reported in T2DM and CAD. However effects of troglitazone therapy (TRO) on myocardial IR remain uncertain. To clarify heart and skeletal muscle and whole body IR in T2DM with...

PURPOSE The purpose of this study was to explore the perspectives of adolescents diagnosed with type 2 diabetes mellitus (T2DM) in terms of how youths conceptualized the effect of T2DM on daily life, adjustment to the illness, and motivation related to diabetes self-care management. The aims of the study were to gather essential information in order to develop appropriate intervention technique...

Type 2 diabetes mellitus (T2DM) can cause multidimensional cognitive deficits, among which working memory (WM) is usually involved at an early stage. However, the neural substrates underlying impaired WM in T2DM patients are still unclear. To clarify this issue, we utilized functional magnetic resonance imaging (fMRI) and independent component analysis to evaluate T2DM patients for alterations ...