Arsenic is an environmentally ubiquitous health hazard due to its toxicity combined with natural abundance and heavy industrial applications. Due role in cardiovascular disease, neurotoxicity, various cancers, it important understand environmental fate of arsenic-containing compounds take steps towards remediation. Sodium arsenite (NaAsO2) one such compound that has been used worldwide as herbi...

A strain of Halomonas bacteria, GFAJ-1, has been claimed to be able to use arsenate as a nutrient when phosphate is limiting and to specifically incorporate arsenic into its DNA in place of phosphorus. However, we have found that arsenate does not contribute to growth of GFAJ-1 when phosphate is limiting and that DNA purified from cells grown with limiting phosphate and abundant arsenate does n...

Harold, F. M. (National Jewish Hospital, Denver, Colo.), and J. R. Baarda. Interaction of arsenate with phosphate-transport systems in wild-type and mutant Streptococcus faecalis. J. Bacteriol. 91:2257-2262. 1966.-Arsenate competitively inhibits the growth of Streptococcus faecalis, primarily by competition with phosphate for a common transport system. Arsenate is itself accumulated by the cell...

Arsenate is a major toxic constituent in arsenic-contaminated water supplies. Saccharomyces cerevisiae was engineered as a potential biosorbent for enhanced arsenate accumulation. The phosphate transporter, Pho84p, known to import arsenate, was overexpressed using a 2μ-based vector carrying PHO84 under the control of the late-phase ADH2 promoter. Arsenate uptake was then evaluated using a resti...

A recent finding of a bacterial strain (GFAJ-1) that can rely on arsenic instead of phosphorus raised the questions of if and how arsenate can replace phosphate in biomolecules that are essential to sustain cell life. Apart from questions related to chemical stability, there are those of the structural and functional consequences of phosphate-arsenate substitutions in vital nucleotides in GFAJ1...

Citation: Tripathi DK, Singh S, Singh VP, Prasad SM, Chauhan DK and Dubey NK (2016) Silicon Nanoparticles More Efficiently Alleviate Arsenate Toxicity than Silicon in Maize Cultiver and Hybrid Differing in Arsenate Tolerance. Front. Environ. Sci. 4:46. doi: 10.3389/fenvs.2016.00046 Silicon Nanoparticles More Efficiently Alleviate Arsenate Toxicity than Silicon in Maize Cultiver and Hybrid Diffe...

Pteris vittata sporophytes hyperaccumulate arsenic to 1% to 2% of their dry weight. Like the sporophyte, the gametophyte was found to reduce arsenate [As(V)] to arsenite [As(III)] and store arsenic as free As(III). Here, we report the isolation of an arsenate reductase gene (PvACR2) from gametophytes that can suppress the arsenate sensitivity and arsenic hyperaccumulation phenotypes of yeast (S...