intradermal injection of autologous serum and plasma elicit a cutaneous reactivity in almost 45-60% of patients with chronic idiopathic urticaria (ciu).   this reactivity is associated with the presence of auto antibodies against ige or ige receptors. this study was carried out to compare the cutaneous reactivity of autologous serum and plasma skin tests in a series of patients with ciu for dia...

aeroallergens continue to have a key role in the pathogenesis of asthma and allergic diseases and have recently received increased attention in medical research throughout the world. the prevalence of aeroallergens vary in different regions, depending on the type of climate. the aim of the present study was to determine prevalence of the sensitivity to aeroallergens among patients with asthma a...

OBJECTIVE To describe the outcomes of clinical evaluation, skin testing, and vaccine challenge in adolescent schoolgirls with suspected hypersensitivity to the quadrivalent human papillomavirus vaccine introduced in Australian schools in 2007. DESIGN Retrospective cohort study. SETTING Two tertiary paediatric allergy centres in Victoria and South Australia, Australia. PARTICIPANTS 35 scho...

Skin prick tests are the first investigation in allergy diagnostics and their use is described in all the guidelines on atopic eczema. However, the clinical usefulness of skin prick tests is the subject of great debate. On the one hand, skin prick tests allow the identification both of individuals at risk for food allergy and of the allergen inducing the eczematous flare. On the other hand, whe...

specific local immunotherapy has been recently introduced as an alternative to classic subcutaneous immunotherapy in treatment of allergic rhinitis. in this study, the effects of sublingual immunotherapy (slit) on symptoms and medication score and skin prick test evaluation of patients with allergic rhinitis were investigated. in this placebo controlled trial, twenty four patients aged 5-18 yea...

Results Case A 30-year-old Thai woman, who presented with a history of angioedema for 6 months. Her angioedema involved lip, eyelid and hand swelling. She was referred to our Allergy Clinic for further investigation. It was found that her symptoms of angioedema usually occurred in 30 minutes after ingesting navel orange and disappeared after 1-2 hours later. She favored in navel orange and she ...

BACKGROUND Current statistics show that approximately 10% of patients claim to be allergic to penicillin yet only 10% of these have demonstrable allergy. The most appropriate and cost-effective antibiotics are sometimes withheld on the basis of patient history of drug allergy. OBJECTIVE Investigation of IgE hypersensitivity and delayed hypersensitivity in patients with a history of penicillin...

RATIONALE The use of beta-blockers is a relative contraindication in allergen skin testing yet there is a paucity of literature on adverse events in this circumstance. We examined a population of skin tested patients on beta-blockers to look for any adverse effects. METHODS Charts from 2004-2008 in a single allergy clinic were reviewed for any patients taking a beta-blocker when skin tested. ...

BACKGROUND Allergists commonly perform intradermal skin testing (IDST) after negative skin-prick testing (SPT) to comprehensively diagnose environmental allergic sensitization. However, with the availability of modern methods to detect serum-specific immunoglobulin E (ssIgE), it is unclear if ssIgE testing could substitute for IDST. OBJECTIVE To determine the efficacy of ssIgE testing and IDS...