نتایج جستجو برای: sequence homology

تعداد نتایج: 435400  

Journal: :Topology and its Applications 2017

1995
Eddy Mayoraz Inna Dubchak Ilya Muchnik

A method of quantitative comparison of two classi cations rules applied to protein folding problem is presented. Classi cation of proteins based on sequence homology and based on amino acid composition were compared and analyzed according to this approach. The coe cient of correlation between these classi cation methods and the procedure of estimation of robustness of the coe cient are discussed.

1998
WEIPING LI

We develop a method of calculation for the symplectic Floer homology of composite knots. The symplectic Floer homology of knots defined in [15] naturally admits an integer graded lifting, and it formulates a filtration and induced spectral sequence. Such a spectral sequence converges to the symplectic homology of knots in [15]. We show that there is another spectral sequence which converges to ...

2006
Cristian Ruiz Ana Blanco Javier Pastor Pilar Diaz

The lipolytic system of Bacillus megaterium 370 was investigated, showing the existence of at least two secreted lipases and a cell-bound esterase. A gene coding for an extracellular lipase was isolated and cloned in Escherichia coli. The cloned enzyme displayed high activity on short to medium chain length (C4^C8) substrates, and poor activity on C18 substrates. On the basis of amino acid sequ...

Journal: :Proceedings. International Conference on Intelligent Systems for Molecular Biology 1995
Eddy Mayoraz Inna Dubchak Ilya B. Muchnik

A method of quantitative comparison of two classifications rules applied to protein folding problem is presented. Classification of proteins based on sequence homology and based on amino acid composition were compared and analyzed according to this approach. The coefficient of correlation between these classification methods and the procedure of estimation of robustness of the coefficient are d...

Journal: :avicenna journal of medical biotechnology 0

toxoplasmosis is an infection caused by the protozoan parasite toxoplasma gondii (t.gondii) throughout the world. although usually asymptomatic, the infection can cause serious medical problems in immunocompromised individuals and fetuses. toxoplasmosis also causes considerable economic loss because of abortion in livestock. dna vaccination is a promising approach against intracellular parasite...

Journal: :iranian journal of basic medical sciences 0
fatemeh baghbani 1department of medical genetics, school of medicine, mashhad university of medical sciences, mashhad, iran reza raoofian 1department of medical genetics, school of medicine, mashhad university of medical sciences, mashhad, iran mohammad hasanzadeh nazarabadi 1department of medical genetics, school of medicine, mashhad university of medical sciences, mashhad, iran tayebeh hamzehloei 1department of medical genetics, school of medicine, mashhad university of medical sciences, mashhad, iran mohammad soukhtanloo department of clinical biochemistry, school of medicine, mashhad university of medical sciences, mashhad, iran mansur heidari of medical genetics, school of medicine, tehran university of medical sciences, tehran, iran

objective(s): hypoxia is a serious challenge for treatment of solid tumors. this condition has been manifested to exert significant therapeutic effects on glioblastoma multiform or (who) astrocytoma grade iv. hypoxia contributes numerous changes in cellular mechanisms such as angiogenesis, metastasis and apoptosis evasion. furthermore, in molecular level, hypoxia can cause induction of dna brea...

Journal: :Bioinformatics 2002
Melissa S. Cline Richard Hughey Kevin Karplus

MOTIVATION Protein sequence alignments have a myriad of applications in bioinformatics, including secondary and tertiary structure prediction, homology modeling, and phylogeny. Unfortunately, all alignment methods make mistakes, and mistakes in alignments often yield mistakes in their application. Thus, a method to identify and remove suspect alignment positions could benefit many areas in prot...

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