Human breast milk can be considered as “ideal” food for the correct development of newborn babies and, for those that are not breast-fed, formula milk has to be used instead. Ideally, the composition of such formula milk preparations should closely resemble that of maternal human milk. Considerable differences between both in the total content of trace elements such as Fe, Cu, Se, Zn, and I and...

Distribution of Cu, Zn, Cd, Ag, Hg, and Se were determined in hepatocytosol of northern fur seals (Callorhinus ursinus), black-footed albatrosses (Diomedea nigripes), and Dall's porpoises (Phocoenoides dalli). Copper, Zn, and Cd were accumulated preferentially in metallothionein (MT) fraction and their contents in MT fraction increased with the amounts in the hepatocytosol. Silver was bound to ...

Abstract Objectives Durvalumab (Imfinzi ® ), a PD-L1 monoclonal antibody (mAb) medication is available as concentrate (50 mg/mL) for solution infusion. The summary of product characteristics provides information about the physicochemical stability ready-to-administer durvalumab preparations (vehicle 0.9 % NaCl, G5%), but not after first opening. objective this study was to determine opening ove...

Objectives: to translate, adapt cross-culturally and validate into Brazilian Portuguese the following instrument: "Self-assessment of communication skills and professionalism in residents" for the nursing professional, and to determine if personal characteristics and performance of the nurse interfere in the self-assessment about professionalism and interpersonal communication. Method: quanti...

Modular chiral dendrimers with monodentate phosphoramidite ligands located at the core were synthesized and applied in the Rh-catalyzed asymmetric hydrogenations, afforded unprecedented enhancement of enantioselectivity.

Berhane Beyene Mentaye*, Mebratu Zelalem, Angelo Asha, Yosef Tiruneh, Aklog Afework, Menberu Tedela, Tsion Bezuneh, AlmazG/senbet, Femi Oyewole, Almaz Abebe, Tilahun Woldemichael and Oyewale Tomori Polio Laboratory and Virology and Ricketisiology Team, Ethiopian Health and Nutrition Research Institute, Disease Prevention and Control Department, Ministry of Health of Ethiopia, World Health Organ...

MARVIN REID,1,2 ASHA BADALOO,2 TERRENCE FORRESTER,2 JOHN F. MORLESE,1,2 MARGARET FRAZER,1 WILLIAM C. HEIRD,1 AND FAROOK JAHOOR1 1United States Department of Agriculture/Agricultural Research Service, Children’s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030; and 2Tropical Metabolism Research Unit, University of the West Indies, Mona, Kingst...

The inclusion complexes of a new family of nonionic amphiphilic calix[4]arenes with the anti-inflammatory hydrophobic drugs naproxen (NAP) and ibuprofen (IBP) were investigated. The effects of the alkyl chain's length and the inner core of calix[4]arenes on the interaction of the two drugs with the calix[4]arenes were explored. The inclusion complexes of Amphiphiles 1a-c with NAP and IBP increa...

The aim of this study was to develop optimized sucrose ester (SE) stabilized oleanolic acid (OA) nanosuspensions (NS) for enhanced delivery via wet ball milling by design of experiments (DOE). In this study, SEOA NS batches were prepared by wet ball milling method. Mean particle sizes and polydispersity indices were determined using a nanosizer. The percent encapsulation efficiency, saturation ...