نتایج جستجو برای: rat pup
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A translational need exists to understand and predict vancomycin-induced kidney toxicity. We describe: (i) a vancomycin high-performance liquid chromatography (HPLC) method for rat plasma and kidney tissue homogenate; (ii) a rat pharmacokinetic (PK) study to demonstrate utility; and (iii) a catheter retention study to enable future preclinical studies. Rat plasma and pup kidney tissue homogenat...
We present simultaneous optical and near-infrared high angular resolution observations of the close Herbig Ae/Be binary star NX Pup which is associated with cometary globule 1. The reconstructed images have a diffraction–limited resolution of 62 mas in V, 75 mas in R (speckle masking reconstruction), and 115 mas in H, 156 mas in K (adaptive optics + post–processing). Compared to previous result...
Using multiple murine foster-nursing protocols, thereby eliminating placental transfer and allowing a distinction between dam- and pup-derived cells, we show that foster nursing by an immunized dam results in development of CD8(+) T cells in nonimmunized foster pups that are specific for Ags against which the foster dam was immunized (Mycobacterium tuberculosis or Candida albicans). We have dub...
OBJECTIVE To perform and confirm a simplified diagnostic indicators scoring system for predicting peptic ulcer perforation (PUP). METHODS A case-control study was conducted including 812 consecutive patients with PUP from retrospective medical records. Each diagnostic indicator measurable at the time of admittance was analyzed by a multiple regression. Stepwise logistic regression was applied...
Pup (prokaryotic ubiquitin-like protein) from Mycobacterium tuberculosis is the first ubiquitin-like protein identified in non-eukaryotic cells. Although different ubiquitin-like proteins from eukaryotes share low sequence similarity, their 3D (three-dimensional) structures exhibit highly conserved typical ubiquitin-like folds. Interestingly, our studies reveal that Pup not only shares low sequ...
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