to study the newly mentioned significance of the obstructive lesion morphology in coronary artery disease (cad), a study has been designed to compare this feature between patients having stable angina (sa) or unstable angina (ua) who underwent coronary angiography in tehran heart institute. study objectives were detection of the angina producing artery (ap a) and its morphologic lesion type, de...

s | 35 Abstract Due to familial factors, younger siblings of children with Autism Spectrum Disorder (ASD) are at an increased risk for developing the disorder1,2. Although behavioral symptoms of ASD typically emerge during a child’s second year,3 recent work on younger siblings demonstrates that prodromal features of ASD are present already within the first months of life. These features includ...

BACKGROUND & OBJECTIVES Detection of prodromal symptoms among patients with mania by their immediate relatives has been seldom examined. We carried out this study to examine the ability to detect and report prodromol symptoms of manic relapses by patients themselves and their relatives. METHODS The ability of patients and their relatives to detect prodromal symptoms was examined among 60 remi...

s | 35 Abstract Due to familial factors, younger siblings of children with Autism Spectrum Disorder (ASD) are at an increased risk for developing the disorder1,2. Although behavioral symptoms of ASD typically emerge during a child’s second year,3 recent work on younger siblings demonstrates that prodromal features of ASD are present already within the first months of life. These features includ...

OBJECTIVE The Structured Interview for Prodromal Syndrome (SIPS) from Yale University is intended to diagnose prodromal syndrome of psychosis and to measure the severity of prodromal symptoms. Here, a Korean version of SIPS is presented, and its reliability, validity, and factor structures are examined using a representative Korean sample. METHODS The Korean version of SIPS was administered t...

Although the diagnosis of Parkinson's disease (PD) remains anchored around the cardinal motor symptoms of bradykinesia, rest tremor, rigidity and postural instability, it is becoming increasingly clear that the clinical phase of the disease is preceded by a long period of neurodegeneration, which is not readily evident in terms of motor dysfunction. The neurobiological mechanisms that underpin ...

While a great deal of research has been conducted on prodromal risk syndromes in relation to help-seeking individuals who present to the clinic, there is a lack of research on prodromal risk syndromes in the general population. The current study aimed first to establish whether prodromal risk syndromes could be detected in non-help-seeking community-based adolescents and secondly to characteriz...

BACKGROUND AND PURPOSE Prompt recognition of stroke symptoms is critical to timely treatment and women have increased delay to treatment. Women may be more likely to present with atypical symptoms, but this hypothesis has not been extensively evaluated. METHODS We examined gender differences in the prevalence of presenting and prodromal stroke symptoms among 1107 consecutive patients hospital...

Recent findings suggest that Alzheimer's disease (AD) is a disconnection syndrome characterized by abnormalities in large-scale networks. However, the alterations that occur in network topology during the prodromal stages of AD, particularly in patients with stable mild cognitive impairment (MCI) and those that show a slow or faster progression to dementia, are still poorly understood. In this ...