BBB blood-brain barrier BMEC brain microvascular (capillary) endothelial cells CBSA cationic bovine serum albumin CdTe cadmium tellurium CTAB trimethylammonium bromide DRG dorsal root ganglia HSA human serum albumin ip intraperitoneal iv intravenous MWCNT multi-walled carbon nanotube PAMAM poly(amidoamine) PBCA polybutylcyanoacrylate PEG polyethylene glycol PLA poly(lactide) PLGA poly(lactic-co...

Amphotericin B (AmB)/poly(lactic acid)-b-poly(ethylene glycol) (PLA-b-PEG) nanoparticles coated with polysorbate 80 (Tween-80) were prepared by nanoprecipitation for transport across the blood-brain barrier (BBB). The effects of Tween-80 on the size and distribution, entrapment efficiency and release behavior of AmB/PLA-b-PEG nanoparticles were investigated. Furthermore, the brain targeting and...

Cancer chemotherapy can benefit from the combination of different anticancer drugs. Here, we prepared doxorubicin (Dox)- and thioridazine (Thio)-coloaded methoxy poly(ethylene glycol)-poly(l-lactic acid) (MPEG-PLA) nanoparticles (NPs) for breast cancer therapy. These NPs have an average particle size of 27 nm. The drug loading efficiencies of Thio and Dox are 4.71% and 1.98%, respectively. Comp...

Technology controlling of material surface wettability is important for imparting functionality to the material, and thought lead development useful devices in medical environmental fields. Devices using Poly（lactic acid）（PLA）are sustainable, because PLA derived from renewable resources like corn starch. Therefore, by examining conditions processing super water-repellent PLA, with low impact ca...

The superlative mechanical properties of graphene-based materials make them the ideal filler materials for polymer composites reinforcement. Two types of graphene-based materials, graphene nanoplatelets (xGnP) and reduced graphene oxide (rGO), were used as nanofiller in poly(lactic acid) (PLA) polymer matrix, as well as plasticized PLA. The addition of rGO into PLA or plasticized PLA substantia...

The poly(lactic acid)/ethylene methyl acrylate copolymer (PLA/EMA) blends were melt blended with by a twin-screw extruder. The phase morphologies, mechanical, and rheological properties of the PLA/EMA blends with three weight ratios were investigated. The results showed that the addition of EMA improves the toughness of PLA at the expense of the tensile strength to a certain degree. All the PLA...

The aim of this work was to estimate the biodegradation of a co-extruded starch/poly(lactic acid) polymeric material using a vermiculite based inert solid medium which could simulate compost medium and enable us to achieve complete carbon balances. At the end of the test the mineralisation rate was compared to those obtained for coextruded starch/poly(lactic acid) polymeric material degradation...

Interfacial localization of conductive fillers in a cocontinuous immiscible polymer blend is an efficient way improving the electrical and thermal conductivities composite. Conductive path formation at interface structure expected to provide high conductivity by smaller amount filler, which can be used for applications as materials. In this study, biobased poly(lactic acid) (PLA) was blended wi...

Furanoate polyesters are emerging as promising bioderived polymers that could replace petrochemical-derived in several applications, for example, the textile field. Here, sustainable and fully fibers wet-spun by blending poly(lactic acid) (PLA) poly(pentamethylene 2,5-furanoate) (PPeF), with up to 50 wt% of PPeF. PLA/PPeF blends result immiscible, PPeF domains homogeneously distributed within P...

Poly (lactic acid) (PLA) is an important biodegradable plastic with unique properties. However, its widespread application hindered by low miscibility and suboptimal degradation To overcome these limitations, we investigated the mechanical, thermal, properties of PLA poly (butylene sebacate-co-terephthalate) (PBSeT) blends in presence (ethylene oxide) (PEO). Specifically, this study aimed to id...