نتایج جستجو برای: phylogenetic approaches
تعداد نتایج: 491599 فیلتر نتایج به سال:
TreeFam (http://www.treefam.org) was developed to provide curated phylogenetic trees for all animal gene families, as well as orthologue and paralogue assignments. Release 4.0 of TreeFam contains curated trees for 1314 families and automatically generated trees for another 14,351 families. We have expanded TreeFam to include 25 fully sequenced animal genomes, as well as four genomes from plant ...
Entropy and compression have been used to distinguish fetuses at risk of hypoxia from their healthy counterparts through the analysis of Fetal Heart Rate (FHR). Low correlation that was observed between these two approaches suggests that they capture different complexity features. This study aims at characterizing the complexity of FHR features captured by entropy and compression, using as refe...
In this paper we consider the modern theory of the Bayesian brain from cognitive neurosciences in the light of recommender systems and expose potentials for our community. In particular, we elaborate on noisy user feedback and the thus resulting multicomponent user models, which have indeed a biological origin. In real user experiments we observe the impact of both factors directly in a repeate...
The increasing availability of complete genome sequences and the development of new, faster methods for phylogenetic reconstruction allow the exploration of the set of evolutionary trees for each gene in the genome of any species. This has led to the development of new phylogenomic methods. Here, we have compared different phylogenetic and phylogenomic methods in the analysis of the monophyleti...
Protein-protein interaction plays key role in predicting the protein function of target protein and drug ability of molecules. The majority of genes and proteins realize resulting phenotype functions as a set of interactions. The in vitro and in vivo methods like affinity purification, Y2H (yeast 2 hybrid), TAP (tandem affinity purification), and so forth have their own limitations like cost, t...
Metabolite-content (MC) refers to all small molecules which are the products or intermediates of metabolism within an organism. The metabolite-contents of plants which involve numerous secondary metabolites are highly related to their nutritional and medicinal features. Previous researches have confirmed that phylogeny-guided approaches have been seen as one of the timeefficient and informative...
Phylogenetic analysis requires alignment of gene or protein sequences. Some regions of genes evolve fast and suffer numerous insertion and deletion events and cannot be aligned reliably with automatic alignment algorithms. Such regions of intrinsically uncertain alignment are currently detected and deleted manually before performing phylogenetic analysis. We present the results of a machine lea...
Motivation The computational investigation of DNA binding motifs from binding sites is one of the classic tasks in bioinformatics and a prerequisite for understanding gene regulation as a whole. Due to the development of sequencing technologies and the increasing number of available genomes, approaches based on phylogenetic footprinting become increasingly attractive. Phylogenetic footprinting ...
Good taxonomic practice permits not only to adequately document the rapidly diminishing biodiversity of our planet (Wheeler 2008), but also let us set the foundations for phylogenetic assessments among groups of taxa, allowing a more deeply and proper understanding of the biota (Wheeler 2007). Therefore, any taxonomic problems will hinder not only phylogenetic approaches but conservation effort...
Macroevolutionary trends traditionally are studied by fossil analysis, comparative morphology or evo-devo approaches. With the availability of genome sequences and associated data from an increasing diversity of taxa, it is now possible to add an additional level of analysis: genomic phylostratigraphy. As an example of this approach, we use a phylogenetic framework and embryo expression data fr...
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