BACKGROUND We retrospectively evaluated the efficacy and toxicity of gross tumor volume (GTV) mean-dose-optimized and real-time motion-compensated robotic stereotactic body radiation therapy (SBRT) in the treatment of liver metastases. METHODS Between March 2011 and July 2015, 52 patients were treated with SBRT for a total of 91 liver metastases (one to four metastases per patient) with a med...

BACKGROUND A deregulated energy metabolism is a hallmark of malignant disease that offers possible future targets for treatment. We investigated the prognostic value of the glycolytic enzymes glyceraldehyde 3-phosphate dehydrogenase (GAPDH) and pyruvate kinase type M2 (PKM2), mitochondrial β-F1-ATPase (ATP5B) and the bioenergetic cellular (BEC) index in advanced ovarian cancer. METHODS Fresh ...

Savannakhet Province, Lao People’s Democratic Republic (PDR), is a small area that is connected to Thailand, other areas of Lao PDR, and Vietnam via road No. 9. This province has been increasingly affected by carbon dioxide (CO2) emitted from the transport corridors that have been developed across the region. To determine the effect of the CO2 increases caused by deforestation and emissions, th...

Private finance initiative (PFI), as a form of public/private partnership (PPP), helps to contract the private sector to governmental projects. In contrast to traditional public financed projects, PFI projects are procured by allowing a private sector entity to take the responsibility to design, build, finance, and operate (DBFO) an asset for a contract period of up to several decades. Moreover...

The ubiquitin-proteasome system degrades most intracellular proteins, including misfolded proteins. Proteasome functional insufficiency (PFI) has been observed in proteinopathies, such as desmin-related cardiomyopathy, and implicated in many common diseases, including dilated cardiomyopathy and ischemic heart disease. However, the pathogenic role of PFI has not been established. Here we created...

BACKGROUND & OBJECTIVES Several physiological changes affecting physical fitness occur in humans whenever they are exposed to extremes of environments such as heat, cold and high altitude (HA). The present study was undertaken to evaluate effect of stay in desert and HA on physical fitness and body composition of physically active individuals. METHODS Study was conducted on three groups of ma...

To the best of our knowledge, there is the lack of sufficient information concerning bamboo pellets. In the preliminary research, bamboo pellets showed a low bulk density which could not meet requirement of Pellet Fuels Institute Standard Specification for Residential/Commercial Densified (PFI). To improve its bulk density, pellets were manufactured using mixtures of bamboo and pine particles a...

The effectiveness of platinum re-treatment in relapsed ovarian cancer depends on relapse-free/treatment-free intervals. Platinum agents can be effectively readministered to platinum-sensitive patients (relapsing >12 months after platinum), but efficacy is lower in partially platinum-sensitive (PPS) disease (relapsing 6-12 months after platinum). There is no clear standard treatment challenging ...

Purpose: The article presents an assessment of the situation business enterprises during COVID-19 pandemic. Design/Methodology/Approach: analysis uses Pandemic Fear Index (PFI) and more detailed analyses based on Business Tendency Surveys (BTS). proposed PFI considers critical factors in a pandemic, such as reported cases illness death government actions that restrict operations. Findings: stud...