Meme dışı Paget hastalığı, kaşıntı, ağrı ve egzema gibi iyi huylu hastalıklarla ortak belirtilere sahip olan nadir bir malign neoplazidir. Vulvar hastalık, genellikle postmenopozal kadınlarda etkilenen bölge üzerinde kabuklanma veya ülserasyonlu yavaş büyüyen tanımlanmış kaşıntılı plak olarak görülür. Bu, tanıda gecikmeye sonuç daha kötü prognoza yol açar.Kesin tanı, hücrelerini gösteren vulva ...

The Pan African Medical Journal. 2017;26:65. doi:10.11604/pamj.2017.26.65.8463 This article is available online at: http://www.panafrican-med-journal.com/content/article/26/65/full/ © Saoussane Kharmoum et al. The Pan African Medical Journal ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses...

Extramammary Paget disease (EPD) is a rare malign neoplasm that may affect the vulva and has manifestations common to benign diseases such as itching, pain and eczema. This leads to delay in diagnosis and consequent worse prognosis. The definitive diagnosis is obtained by biopsy of the vulva, which shows Paget cells. The treatment of choice is wide excision with margins, which leads to sequelae...

BACKGROUND Clear cell papulosis is a rare condition that has been reported in 14 children, all but 1 of whom are of Asian descent. It was first described in 1987 and is thus named because of the presence of clear cells in the epidermis. OBSERVATION We describe the cases of 3 Hispanic children in the United States with clear cell papulosis. All 3 patients presented with multiple grouped, oval,...

Pagkt, F. R. S.?The first case was that of a man who fell, about a month ago, on his great trochanter, receiving no other injury than a severe bruise. Mr. Paget insisted on the importance of treating such cases by prolonged rest in bed, as the best means known for averting the acute atrophy of the head and neck of the femur, which too often follows an injury apparently so trivial. After mention...

Paget-Schroetter syndrome is thrombosis of the axillary-subclavian vein that is associated with strenuous and repetitive activity of the upper extremities. Overuse of the arm coupled with external compression results in microtrauma in the intima of the subclavian vein, resulting in the activation of the coagulation cascade. Diagnosis is usually made by Doppler ultrasound and the treatment invol...

A Doença de Paget do mamilo é uma manifestação incomum câncer mama, sendo mais prevalente em mulheres na 6ª década vida, no período da pós-menopausa. Geralmente, tal patologia pode estar associada ao carcinoma intraductal mamário. Sua principal clínica a presença lesão eczematosa e pruriginosa mamilar, longa data que não apresenta melhora, apesar terapias tópicas dermatológicas. Relatamos o cas...