نتایج جستجو برای: p46
تعداد نتایج: 204 فیلتر نتایج به سال:
Method Children with asthma who were followed in our outpatient department of pediatric allergy unit were consecutively recruited. Asthma severity was graded according to NAEPP guidelines. Patients were categorized into two groups; children with intermittent and mild persistent asthma formed Group 1 (mild asthma) whereas children with moderate and severe persistent asthma formed Group 2 (severe...
Natural killer (NK) cells play an important role in hepatitis B virus (HBV) infection control, and are regulated by a complex network of activating and inhibitory receptors. However, NK cell activity in HBV patients remains poorly understood. The objective of this study was to investigate the phenotypic and functional characteristics of circulating NK cells in patients during different chronic ...
CD9, a member of the tetraspanin family, has been shown to be involved in a range of cellular activities, including migration, proliferation and adhesion, but the molecular mechanisms by which it mediates such events is unclear. Here, we found that anti-CD9 monoclonal antibody ALB6 inhibited cell proliferation, reduced cell viability and induced not only morphological changes specific to apopto...
توزیع درآمد به دلیل داشتن اثرات اقتصادی و اجتماعی همواره مورد توجه اقتصاددانان بوده است، در این تحقیق تاثیر توسعه بازار پول بر توزیع درآمد در ایران را طی بازه زمانی 1345 تا 1385 با استفاده از الگوی خودرگرسیونی با وقفه گسترده (ardl) مورد آزمون قرار می دهیم. نتایج، نشان دهنده این است که توسعه بازار پول در بلندمدت و کوتاه مدت سبب کاهش نابرابری درآمد می شود. همچنین نرخ باسوادی و رشد اقتصادی نابرابر...
IL-16 has been reported as a modulator of T cell activation and was shown to function as chemoattractant factor. The chemotactic activity of IL-16 depends on the expression of CD4 on the surface of target cells, but the intracellular signaling pathways are only now being deciphered. This report describes IL-16 as an additional activator of the stress-activated protein kinase (SAPK) pathway in C...
It has recently been shown that T-cell signal transduction molecules are altered in tumor-bearing mice. We have examined the expression of NF.cB/Rel family proteins in T-cells from mice bearing Renca, a munne renal carcinoma. T-cells from Renca-bearing mice expressed undetectable levels of nuclear c-Rel, NF.cB p65, and p50; however two shorter forms of p50 (p48 and p46), truncated at the M12-te...
RbAp46 and RbAp48 (pRB-associated proteins p46 and p48, also known as RBBP7 and RBBP4, respectively) are highly homologous histone chaperones that play key roles in establishing and maintaining chromatin structure. We report here the crystal structure of human RbAp46 bound to histone H4. RbAp46 folds into a seven-bladed beta propeller structure and binds histone H4 in a groove formed between an...
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