نتایج جستجو برای: one locus mismatch
تعداد نتایج: 2075455 فیلتر نتایج به سال:
The genome-wide accumulation of DNA replication errors known as microsatellite instability (MSI) is the hallmark lesion of DNA mismatch repair (MMR)–deficient cancers. Although testing for MSI is widely used to guide clinical management, the contribution of MSI at distinct genic loci to the phenotype remains largely unexplored. Here, we report that a mononucleotide (T/U)16 tract located in the ...
Background and aims: Various factors affect the safety performance of employees and safety locus of control (SLOC) is one of the main determinants. People with an internal locus of control believe that they can control events and conditions and People with an external locus of control believe that events caused by factors such as chance, fate, environment and performance of other people. Theref...
Introduction: One of the reasons causing academic failure among students is disregarding factors affecting learning. The aim of this study was to determine the relationship between academic achievement of nursing and midwifery students and their learning characteristics including study style, control locus, and self-organized learning factors which are modifiable issues in learning. Methods: I...
Background and purpose: Dietary adherence is a major challenge in management of diabetes and is usually lower in women with gestational diabetes. One of the main factors in following medical instructions is the health locus of control. Materials and methods: This descriptive and analytic study was performed in women with gestational diabetes and dietary modifications attending health centers ...
background: hereditary non-polyposis colorectal cancer (hnpcc) is a common hereditary cancer predisposing syndrome has molecular and clinicopathological features still have remained ambiguous within iranian populations. we discuss in this article some molecular and clinicopathological features of the condition. methods: the study was a descriptive retrospective and designed on 1659 colorectal c...
Competition between phonologically similar sequences in an utterance is one of the major causes for speech production errors. Additionally, phonological competition has been found to increase planning time and slow down speech rate in CVC word pairs. The aims of this study are to investigate the timecourse of phonological competition by employing different tasks and by a detailed gestural analy...
in an attempt to characterize theileria parva parasites circulating in south sudan cattle , polymerase chain reaction (pcr)-based assays were carried out using four single copy encoding antigen genes p104, pim, p150 and p67 in addition to one microsatellite ms321. a total of 20 bovine dna samples from two locations in south sudan were included in this study, in addition to two references strain...
Microsatellites are tandem repeats of simple polymorphic sequences randomly distributed in non-coding regions of DNA. They can be used in cancer genetics and indirect cancer diagnosis and can help unraveling the genetic basis of tumor formation and progression of cancer. Breast cancer is a complex disease in which numerous genetic alterations occur. The knowledge of specific genetic changes and...
Systemic cisplatin-based chemotherapy cures > or =90% of patients with metastatic germ cell tumors (GCTs). The biological basis of this exquisite chemo-sensitivity and the resistant phenotype encountered in 10-15% of patients with GCT is yet unclear. A defective mismatch repair pathway leading to microsatellite instability (MSI) has been related to resistance to cytotoxic drugs. We investigated...
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