We read with interest the recent article by Memon et al. (1). In this study involving the Belgian population, the Helicobacter pylori vacuolating cytotoxin (vacA) genotype was shown to be a strong marker for gastric cancer and duodenal ulcer disease. The finding that certain H. pylori vacA-positive strains are associated with key clinical outcomes is important, but available data are unfortunat...

BACKGROUND It remains unclear whether the low incidence of gastric cancer in Indonesia is due to low infection rates only or is also related to low Helicobacter pylori pathogenicity. We collected H. pylori strains from the five largest islands in Indonesia and evaluated genetic virulence factors. METHODS The genotypes of H. pylori virulence factors were determined by polymerase chain reaction...

Copyright © 2013 P.-I Hsu and N.-J. Peng. is is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. As a general rule for the treatment of infectious diseases, clinicians should prescribe anti-H. pylori regimens that have a per-protocol erad...