UNLABELLED THE AIM of our study was to evaluate the prognostic significance of p53 protein immunoreactivity for prostate cancer and to determine whether p53 immunoreactivity correlates with the Gleason tumor grade in primary adenocarcinoma. Prostate fragments were fixed in 10% formalin, paraffin-embedded, sectioned and standard Hematoxylin-Eosin stained, then examined using histological grade (...

epithelial myoepithelial carcinoma is a rare biphasic low grade neoplasm of salivary glands; it most commonly occurs in the parotid gland but can also arise in minor salivary glands. here a case of 58-year-old female presented with left cheek swelling of one-year duration. ct scan revealed a localized submandibular salivary gland tumor mass not involving surrounding tissues. histological examin...

INTRODUCTION The aim of this study was to investigate the probable differences in P53 expression between papillary urothelial neoplasm of low malignant potential (PUNLMP) and varying grades of transitional cell carcinoma (TCC) of the bladder. MATERIALS AND METHODS Ten biopsy specimens of the patients with PUNLMP, 20 of the patients with papillary low-grade TCC, 20 of those with invasive high-...

BACKGROUND Hepatitis B virus (HBV) plays well-known roles in tumorigenesis of hepatocellular carcinoma (HCC) in infected patients. However, HBV-associated protein status in tumor tissues and the relevance to tumor behavior has not been reported. Our study aimed to examine the expression of HBV-associated proteins in HCC and adjacent nontumorous tissue and their clinicopathologic implication in ...

UNLABELLED Clear cell carcinomas (CCC) of the mullerian system are considered high grade tumors, but morphologically, the cells of CCC show both low and high grade features. The aims of the current study were to categorize CCC into low and high nuclear grade types, correlate their association with endometriosis, and then observe possible variations in pathogenesis based on their expression of p...

Introduction: Describe the profile of patients referred for computed tomography (CT) likely to be scanned with scintigraphy imaging in Togo. Methods: Prospective study carried out from May 15 to August 15 2020 including patients referred for non-traumatic CT scans (excluding strokes) in all the radiology centres in Togo with operational ...

The grading of cancer is a histological method intended to help predict prognosis based on specific morphological features. It typically is based on architectural or cytological features (nuclear grade or number of mitoses), or in some cases, a combination of both. Grading is usually broken down into a spectrum from well differentiated (grade 1) to the most poorly differentiated (grade 3 or 4)....

Background: This study aims to determine the pathologists’ agreement of modified Black nuclear grading system and Holland classification applied to cases of ductal carcinoma in situ (DCIS). Methods: Forty-three cases of breast lesions diagnosed as DCIS were selected to interobserver analysis. Eight pathologists received the same set of digitized images from microscopy of DCIS cases, and answere...

BACKGROUND/AIM There are a lot of studies aiding to the opinion that the involvement degree of axilla lymph nodes grows depending on increase of breast tumor size, and its histological and nuclear grades. The aim of this study was to assess the risk of axillary lymph nodes involvement, as well as the relation between the tumor size, histological and nuclear grades in a group of female patients ...