A number of precautions were taken to ensure the accuracy of the analytical procedures and to avoid artifactual formation of N-nitroso compounds. NDPA (5 ng/g), an NDMA analog which is not normally present in the diets, was added to each powdered sample prior to the vacuum distillation step as an internal (recovery) standard. All reported levels of NDMA and NPYR have been adjusted for the recov...

The brain is a dynamic, flexible network that continuously reconfigures. However, the neural underpinnings of how state-dependent variability of dynamic functional connectivity (vdFC) relates to cognitive flexibility are unclear. We therefore investigated flexible functional connectivity during resting-state and task-state functional magnetic resonance imaging (rs-fMRI and t-fMRI, resp.) and pe...

Soluble fractions of sonicates derived from cell suspensions of some bacteria and yeasts, which contaminate palm sap, enhanced nitrosamine formation when each fraction was incubated, under sterile conditions, at a pH of 7.0 +/- 0.2, with either diphenylamine, dimethylamine or diethylamine and sodium nitrite and glucose as substrates. The intrinsic factor in the extracts, which was responsible f...

Nitrite, added to cured meat for its bacteriological and technological properties, is implicated in the formation of nitroso compounds (NOCs), such as nitrosylheme, nitrosamines nitrosothiols, suspected have a potential impact on human health. The mechanisms involved NOC are studied regard with dose–response relationship nitrite interaction ascorbate cooked model. second cooking stage nitrosati...