Synthesis of a new methoxy dibenzofluorene through alkylation, cyclodehydration and aromatization in a one-pot operation is achieved for the first time. Using this hydrocarbon, a few derivatives are prepared through aromatic nitration, catalytic hydrogenation, coupling reaction with a side chain and reduction. The benzylic position of this hydrocarbon with the side chain is oxidized and reduced...

htvb}+OH--'OHOrhlvb)+H2OT"'OH+Htq [5] These active species of oxygen as well as eand ht.b) would support a wide variety of Ti02 dependent photo-induced catalytic reactions, oxidation, oxidative cleavage, reduction, geometric and valence isomerization, substitution, condensation, and polymerizatien.i) We showed here that NOi is oxidized by・OH and reduced by e', producing NOi and NO, respectively...

Modification of tyrosine residues and formation of 3-nitrotyrosine is one of the most commonly identified effects of reactive nitrogen species on proteins. In this study we evaluated the presence and localization of tyrosine nitration in various ventilatory and limb muscles. We also assessed the contribution of the neuronal (nNOS), the endothelial (eNOS), and the inducible (iNOS) isoforms of ni...

Sulfhydryl reagents, as well as mild hydrogen peroxide oxidation, do not inhibit the activity of yeast phosphoglycerate kinase, indicating that the single thiol group and 3 methionine residues present in the enzyme are not essential for activity. Nitration of phosphoglycerate kinase by tetranitromethane inhibits the enzyme by reaction with a single tyrosine residue. Substrates provide partial p...

An efficient Pd catalyst for the transformation of aryl chlorides, triflates, and nonaflates to nitroaromatics has been developed. This reaction proceeds under weakly basic conditions and displays a broad scope and excellent functional group compatibility. Moreover, this method allows for the synthesis of aromatic nitro compounds that cannot be accessed efficiently via other nitration protocols...

htvb}+OH--'OHOrhlvb)+H2OT"'OH+Htq [5] These active species of oxygen as well as eand ht.b) would support a wide variety of Ti02 dependent photo-induced catalytic reactions, oxidation, oxidative cleavage, reduction, geometric and valence isomerization, substitution, condensation, and polymerizatien.i) We showed here that NOi is oxidized by・OH and reduced by e', producing NOi and NO, respectively...

Abstract The high-throughput automatic sample addition platform technology was applied to the large-scale addition, pretreatment, and synthesis of simple compounds in many fields. With introduction material genome into field high energy energetic materials (HEDMs), (EMG) project is implemented. Completing different reaction types at same time has become key materials. In this study, three commo...

Proteins can be nitrated by air pollutants (NO2), enhancing their allergenic potential. This work provides 15 insight into protein nitration and subsequent decomposition in the presencet of solar radiation. We also investigated 16 light-induced formation of nitrous acid (HONO) from protein surfaces that were nitrated either online with 17 instantaneous gas phase exposure to NO2 or offline by an...

OBJECTIVE To examine in vitro the ability of several drugs to protect against deleterious effects of peroxynitrite, a cytotoxic agent formed by reaction of nitric oxide with superoxide radical, that may be generated in the rheumatoid joint and could cause joint damage. METHODS The ability of several drugs to protect against such possible toxic actions of peroxynitrite as inactivation of alpha...

Abstract Cellulose nitrate (CN) is used in numerous industrial materials, such as propellants, lacquers, and plastics, exploiting its highly flammable, hydrophobic, plastic characters. The downsizing of cellulose fibers may enhance their properties. Although a direct nitration nanofiber (CNF) prospective method for preparing nanosized CN it difficult because the susceptibility CNF to acids. In ...