Atopic dermatitis is the most common chronic inflammatory disease among children in industrialised countries. Many factors influence this disease in a negative way and contact allergy is one such factor. The aim of the study was to examine the frequency of contact allergy among children with the diagnosis atopic dermatitis. Contact allergy was found in 22/82 children (26.8%), the most common fr...

Abstract Allergy to nickel based alloy arch wires, which is largely induced by corrosion behavior, can cause severe problems during the orthodontic treatment. However, no consensus has been reached in comparison of anti-corrosion behavior between Nickel-Titanium (NiTi) and Copper (CuNiTi) wires. Herein, NiTi CuNiTi wires was simultaneously studied artificial saliva under loading stress simulate...

Occupational asthma from nickel sensitivity was confirmed in a male worker (SB) by allergy skin tests and inhalational challenge. In an ammonium sulphate coprecipitation test 63Ni was selectively precipitated from SB plasma indicating antibody with nickel related specificity. Preincubation of 63Ni with human serum albumin (HSA) increased the specificity of the coprecipitation test. Blocking exp...

I am glad to reply to Goldenberg and Jacob’s observations, whom I thank for the kind attention given to my article. As a preliminary consideration, I wish to reiterate that my paper discussed exclusively the exposure to nickel via food; it didn’t discuss the other routes of systemic exposure. It distinguished allergic contact dermatitis (ACD) from systemic nickel allergy syndrome (SNAS) and, wi...

Nickel compounds are prime inducers of contact allergy reactions in humans. To identify the signal transduction pathways mediating the cellular responses to nickel and to elucidate their hierarchy, we performed Affymetrix gene profiling using human primary endothelial cells, which strongly respond to nickel stimulation. Overall, we found 258 significantly modulated transcripts, comprising 140 u...

is more common in women than in men. Conclusions: Approximately 25 chemicals appear to be responsible for as many as one half of all cases of allergic contact dermatitis. These include nickel, preservatives, dyes, and fragrances. in this study Allergic contact dermatitis is more common in women than in men. This predominantly is a result of allergy to nickel, which is much more common in women ...

OBJECTIVE This study was carried out to evaluate the reproducibility, sensitivity, specificity, and reliability of the MELISA Test for detecting metal sensitivity in patients with clinical symptoms of a type IV hypersensitivity to metal. DESIGN Blood from 250 patients was tested in MELISA against up to 20 different metals in 2 to 3 concentrations. The frequency and distribution of metal react...

BACKGROUND In April 2014, the European Chemicals Agency defined the concept of 'prolonged contact with skin' as used in the EU nickel restriction. OBJECTIVES To establish a baseline of nickel-releasing items on the Swedish market conforming with the EU nickel restriction according to the definition of 'prolonged contact' with the skin. METHODS We performed a limited market survey in Stockho...