نتایج جستجو برای: mice model
تعداد نتایج: 2422472 فیلتر نتایج به سال:
Multiple imputation by chained equations (MICE) is the most common method for imputing missing data. In MICE algorithm, can be performed using a variety of parametric and nonparametric methods. The default setting in implementation models to include variables as linear terms only with no interactions, but omission interaction may lead biased results. It investigated, simulated real datasets, wh...
Objective(s): In this study, we aimed to investigate the effects of anti-Fas ribozyme on the apoptosis of T lymphocytes (T cells) in mice model with chronic obstructive pulmonary disease (COPD). Materials and Methods: Male 6-week-old C57BL/6 mice were used to establish the COPD model by exposure to cigarette smoke. The COPD mice were sacrificed for spleen dissection and T cell isolation. T cell...
Multiple Sclerosis (MS) is a neurodegenerative and autoimmune disease that it’s molecular etiology and factors involving in its progression remains unknown. In this study for evaluation effect of mercuric on progression of MS we investigated the additive effect of mercuric sulfide on the brain mitochondrial dysfunction in experimental autoimmune encephalomyelitis (EAE) model of MS in C57BL/6 mi...
Objective Royal jelly is a honey bee secretion that possesses beneficial effects on the nervous system. The present study investigates the effects of royal jelly in reducing convulsion and anxiety in mice. Methods In this experimental study to assess royal jelly's anticonvulsant effects, 25 male albino mice were randomly classified into five groups: control, royal jelly 100 mg/kg, royal jelly ...
Background: It has been reported that vitamin D has broad anti-inflammatory and immunomodulatory effects. Objective: To evaluate the effects of vitamin D on the expression of IL-27 and IL-33 in a model of experimental autoimmune encephalomyelitis (EAE). Methods: EAE was induced in C57BL/6 mice by immunization with myelin oligodendroglial glycoprotein mixed with complete Freund's adjuvant. The m...
rivers and runoff have always been of interest to human beings. in order to make use of the proper water resources, human societies, industrial and agricultural centers, etc. have usually been established near rivers. as the time goes on, these societies developed, and therefore water resources were extracted more and more. consequently, conditions of water quality of the rivers experienced rap...
Multiple Sclerosis (MS) is a neurodegenerative and autoimmune disease that it’s molecular etiology and factors involving in its progression remains unknown. In this study for evaluation effect of mercuric on progression of MS we investigated the additive effect of mercuric sulfide on the brain mitochondrial dysfunction in experimental autoimmune encephalomyelitis (EAE) model of MS in C57BL/6 mi...
Introduction: The use of cell phones is widespread and there are public concerns regarding its possible deleterious effects on human health especially on the pregnancy outcomes. In this study, structural changes of the placenta after applying the cell phone radiation were examined in the mice model. Materials and methods: For this work, 40 pregnant Balb/C mice were randomly allocated to ...
objective(s)cpg oligodeoxynucleotides (cpg odns) have been shown to have potent immunostimulatory adjuvant activity for a wide range of antigens. due to susceptibility of phosphodiester cpg odns (po cpg) to nuclease degradation, nuclease-resistant phosphorothioate cpg odns (ps cpg) were currently utilized in an in vivo model. in this study, according to some recently reported drawbacks with ps ...
objective(s):bone marrow-derived mesenchymal stem cells (bmscs) have attracted significant interest to treat asthma and its complication. in this study, the effects of bmscs on lung pathology and inflammation in an ovalbumin-induced asthma model in mouse were examined. materials and methods:balb/c mice were divided into three groups: control group (animals were not sensitized), asthma group (an...
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