Advances in nanotechnology have seen the development of several microbiocidal nanoparticles displaying activity against biofilms. These applications benefit from one or more combinations of the nanoparticle properties. Nanoparticles may indeed concentrate drugs on their surface resulting in polyvalent effects and improved efficacy to fight against bacteria. Nanodiamonds (NDs) are among the most...

Menthol vapours are irritant to eyes, nose and throat, and ingestion of this chemical has been reported by Von Oetingen (1958)1) to cause abdominal pain, vomiting, staggering gait and sopor. The workers exposed to high concentrations of menthol vapours in an industry manufacturing menthol crystalls from the plant extracted mentha oil complained of drowsiness, headache, nausea and vomiting. Till...

Menthol cigarettes have been found to be more addictive and a higher difficulty of smoking cessation among smokers (1). The impact of menthol cigarette smoking, including nicotine dependence is worrying the public (2-4) and the younger generation (5) globally. Menthol cigarettes are associated with increasing trend of smoking initiation among young non-smoking women (6) and young male adults (7...

468 VOLUME 9 | NUMBER 4 | APRIL 2006 NATURE NEUROSCIENCE mechanism. Although the work by Bandell et al. represents an analysis of channel mutations more extensive than any previously reported, the nature of the error-prone PCRbased mutagenesis, as pointed out by the authors, precluded the generation of amino acid changes that required two or more changes in a single codon. Thus, it is possible ...

BACKGROUND Menthol cigarettes, preferred by African American smokers, have been conjectured to be harder to quit and to contribute to the excess lung cancer burden among black men in the Unites States. However, data showing an association between smoking menthol cigarettes and increased lung cancer risk compared with smoking nonmenthol cigarettes are limited. The Food and Drug Administration is...

The use of tobacco products would not continue without the initiation of their use by youth and adults. Since the vast majority of cigarette smokers begin smoking by age 25, understanding the role of menthol cigarettes in the initiation of smoking in youth (under the age of 18) and young adults (aged 18-25) is especially relevant. Data demonstrate that menthol cigarettes are disproportionately ...

Thymol and menthol are naturally occurring plant derived compounds, which have excellent pharmaceutical and antimicrobial applications. The aim of this work was to evaluate the impact of biofield energy on physical and structural characteristics of thymol and menthol. The control and biofield treated compounds (thymol and menthol) were characterized by X-ray diffraction (XRD), Differential Scan...

Topical menthol gels are classified "topical analgesics" and are claimed to relieve minor aches and pains of the musculoskeletal system. In this study we investigate the acute effect of topical menthol on carpal tunnel syndrome (CTS). We screened 645 slaughterhouse workers and recruited 10 participants with CTS and chronic pain of the arm/hand who were randomly distributed into two groups to re...

Environmental cold is a nonmodifiable hypertension risk factor. Transient receptor potential melastatin subtype 8 (TRPM8) is a cold-sensing cation channel that can be activated by menthol, a compound with a naturally cold sensation in mint. Little is known about the effect of TRPM8 activation on vascular function and blood pressure. Here, we report that TRPM8 is abundantly expressed in the vasc...

BACKGROUND Menthol is a commonly used ingredient in many over the counter cough remedies, but there is little objective evidence as to its efficacy. METHODS Twenty healthy subjects received a cough challenge consisting of five inhalations of 33 mumol citric acid from an air driven dosimeter. The challenge was repeated at hourly intervals for five hours. Five minutes before each challenge subj...