Background Today’s biopharmaceutical industry is under increasing pressure considering cost efficient development. Short timeframes rule the progress starting from the generation of producer cell lines to the establishment of a final production process. Hence, the timescale for optimization of cell culture media is small, but on the other hand it contains high potential for global process impro...

Using the fast measurement of a binary transmission matrix and a digital micromirror device, we demonstrate high-speed interferometric focusing through highly dynamic scattering media with binary intensity modulation. The scanning of speckles for reference optimization gives stable focusing, which can be used for focusing through a fast changing media or two dimensional scanning through a slowl...

1. Abstract In the present work a hybrid optimization method such as the combination of Simulated Annealing and the Levenberg-Marquardt method is used for the solution of the inverse radiative transfer problem of estimating the space dependent albedo in one-dimensional heterogeneous participating media. The unknown function is expanded as a series of known functions, and a finite dimensional op...

This paper presents the definition as well as a number of methods for the solution of a new combinatorial optimization problem, called S-MAMP that has to be solved for the efficient management of a network of media servers. This network of servers can be implemented on top of a closely connected network of workstations as well as on a wide area network of media servers. The problem studied here...

Random media abound in nature and in manmade situations. Examples include porous media, biological materials, and composite materials. A stochastic optimization technique that we have recently developed to reconstruct realizations of random media ~given limited microstructural information in the form of correlation functions! is investigated further, critically assessed, and refined. The recons...

With the pervasion of social media, topic identification in short texts attracts increasing attention in recent years. However, in nature the texts of social media are short and noisy, and the structures are sparse and dynamic, resulting in difficulty to identify topic categories exactly from online social media. Inspired by social science findings that preference consistency and social contagi...

Introduction A series of cell-line specific complex media supplements have been developed for enhancing performance of various vaccine production systems. Created using in-house media optimization methods, these supplements are manufactured using innovative process technology which allows for the formulation of complex and/or chemically defined animal-component free media additives into a singl...

Twitter’s increasing popularity as a source of up to date news and information about current events has spawned a body of research on event detection techniques for social media data streams. Although all proposed approaches provide some evidence as to the quality of the detected events, none relate this task-based performance to their runtime performance in terms of processing speed or data th...

In this paper, we define a novel task named interactive gender inference, which aims to utilize interactive text to identify the genders of two interactive users. To address this task, we propose a two stage approach by well incorporating the dependency among the interactive samples sharing identical users. Specifically, we first apply a standard four-category classification algorithm to get a ...