Abstract. This work is a consequence of studying the (un)relatedness of the principles that allow to implicitly characterize the polynomial time functions (PTIME) under two perspectives. One perspective is predicative recursion, where we take Safe Recursion on Notation as representative. The other perspective is structural proof theory, whose representative can be Light Affine Logic (LAL). A wa...

In spite of its clinical and nutritional importance, l-alanyl-l-glutamine (Ala-Gln) has not been widely used due to the absence of an efficient manufacturing method. Here, we present a novel method for the fermentative production of Ala-Gln using an Escherichia coli strain expressing l-amino acid alpha-ligase (Lal), which catalyzes the formation of dipeptides by combining two amino acids in an ...

Kindergarten children at risk of developing language problems were administered the Florida Kindergarten Screening Battery. A principal components analysis revealed a verbal and a visual-spatial component and subsequent discriminant function analyses a high verbal/low visual-spatial group (LAL: Latent L) and a high visual-spatial/low verbal group (LAP: Latent P). LAL- and LAP-children were cons...

Lysosomal acid lipase (LAL) gene mutations were identified in three patients with cholesteryl ester storage disease (CESD). Direct sequencing of genomic DNA revealed that: patient 1 was a compound heterozygote for a P181L mutation and an A to G3' splice site substitution that causes skipping of exon 7, with a loss of 49 amino acids from LAL (delta 205-253); patient 2 was a compound heterozygote...

In order to gain a deeper understanding of what language assessment literacy (LAL) is and how it can be developed, relevant investigate from the point view different stakeholders (Harding & Kremmel, 2016). As for teacher LAL, this phenomenon has largely been studied teachers’ own perspectives, leaving other stakeholders’ construct underresearched. The current study used an exploratory, qual...

A new compound L soluble in water derived from vitamin B6 was successfully synthesized and characterized. The complex LAl(3+) is a turn-on selective fluorescent probe for histidine in HEPES buffer, with detection and quantification limits of 0.3 μM and 0.6 μM, respectively. The application of the complex LAl(3+) in real urine samples is reported.

The observation that endotoxin caused gelation in extracts of Limulus amebocytes has been expanded to the development of an in vitro kinetic, quantitative chromogenic LAL assay (Kinetic-QCL) for the detection of endotoxin in aqueous fluids. Within the last 15 years, the use of Limulus amebocyte lysate to detect and control the presence of pyrogenic substances in pharmaceuticals and medical devi...

The aim of this study was to describe epidemiological, cytologic and immunophenotypic aspects of acute leukemias (AL) in children diagnosed at IBN SINA University Hospital Center and to determine the concordance between cytology and immunophenotyping results. This is a cross-sectional study conducted in the hematology laboratory of IBN SINA University Hospital Center between June 2012 and May 2...

We established a method of gas chromatography with flame ionization detector (GC-FID) using N-methyl-N-(tert-butyldimethylsilyl) trifluoroacetamide (MTBSTFA) as derivatisation reagent and DL-2,6-diaminopimelic acid (DPA) as internal standard for the determination of lysinoalanine (LAL) in Chinese preserved egg. The derivatisation reaction was under the optimized condition of 75 °C and 30min. Me...