نتایج جستجو برای: ionizing irradiation
تعداد نتایج: 76474 فیلتر نتایج به سال:
The problem of microbial growth in fuels, especially biofuels, is a very important issue. Water necessity for to occur. Unfortunately, it hard exclude all water from fuel systems during daily operations, when biodiesel added the mix. aim this work was investigate impact ionizing radiation on selected properties fatty acids methyl esters order evaluate possibility using irradiation techniques st...
Genomic DNA is organized three-dimensionally in the nucleus, and is thought to form compact chromatin domains. Although chromatin compaction is known to be essential for mitosis, whether it confers other advantages, particularly in interphase cells, remains unknown. Here, we report that chromatin compaction protects genomic DNA from radiation damage. Using a newly developed solid-phase system, ...
We developed a Mitomycin C (MMC)-resistant mouse breast cancer cell subline, R-FM3A, from FM3A parent cells(W-FM3A) by continuous exposure to a concentration of 0.01 microgram/ml MMC for over two months. R-FM3A cells were resistant to MMC and decreased in response to the combined effects of ionizing irradiation and MMC. The resistance to MMC and ionizing irradiation was mediated by a cell-free ...
Bone loss caused by ionizing radiation is a potential health concern for radiotherapy patients, radiation workers and astronauts. In animal studies, exposure to ionizing radiation increases oxidative damage in skeletal tissues, and results in an imbalance in bone remodeling initiated by increased bone-resorbing osteoclasts. Therefore, we evaluated various candidate interventions with antioxidan...
Molecular indicators of the absorbed dose of ionizing radiation are powerful tools in biodosimetry. The studies reported here were undertaken with the motivation to find such a marker among the mo lecules involved in ataxia-telangiectasia mutated kinase- dependent signalling induced by ionizing radiation (ATM-kinase, checkpoint kinase-2, protein p53, and oncoprotein Mdm2). In our previous work ...
Historical Background ABSTRACT Strong sources of radiation became available in the 1950s. Since then, intense ionizing beams have been employed against cancer to destroy or shrink tumors. Today, nearly all radiation treatments for cancer apply high doses to local regions of the body. It is generally believed that radiation in any amount will only damage cells and that the mutated cells could be...
The concept of immunogenic cancer cell death (ICD), as originally observed during the treatment with several chemotherapeutics or ionizing irradiation, has revolutionized the view on the development of new anticancer therapies. ICD is defined by endoplasmic reticulum (ER) stress response, reactive oxygen species (ROS) generation, emission of danger-associated molecular patterns and induction of...
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