PURPOSE To investigate the efficacy of intralesional 20% aspirin injection for treatment of experimental peritoneal endometriosis. METHODS Peritoneal endometriosis was experimentally induced in forty adult nulligravid female rabbits. On day 30 post-endometriosis induction, rabbits were randomly divided to assess early (10 days) and late (20 days) effects of intralesional injection of physiolo...

OBJECTIVE To compare the efficacy of intralesional triamcinolone and topical betamethasone in the management of localized alopecia areata. STUDY DESIGN A randomized trial. PLACE AND DURATION OF STUDY Dermatology OPD, PNS Shifa Hospital, Karachi, from January to June 2013. METHODOLOGY Patients aged 18 - 50 years with localized alopecia areata were included in the study. Exclusion criteria ...

BACKGROUND Alopecia areata of the eyebrows can be difficult to treat. Intralesional triamcinolone or potent topical steroids are considered the mainstay of medical therapy. This case illustrates the results of an experimental hair transplant to the eyebrows following years of modest response to intralesional triamcinolone. OBJECTIVE The aim of this study was to ascertain the benefits of a hai...

IMPORTANCE Oral lesions of pemphigus vulgaris are usually recalcitrant and respond slowly to treatments. Corticosteroid injection is considered to be the most effective local treatment in oral pemphigus vulgaris. However, intralesional corticosteroids are not effective in all remnant lesions. In 3 such patients with pemphigus vulgaris, we evaluated the utility of 2 injections (on days 1 and 15)...

OBJECTIVE To assess the usefulness of contrast-enhanced ultrasound (CEUS) in differentiating malignant from benign gallbladder (GB) diseases. METHODS This study had institutional review board approval. 192 patients with GB diseases from 9 university hospitals were studied. After intravenous bonus injection of a phospholipid-stabilized shell microbubble contrast agent, lesions were scanned wit...

This is a prospective clinical study of 46 ear keloids in 31 patients (with a mean follow-up of 18 months) treated from January 2006 to December 2006 at The Queen Elizabeth Public Hospital, Barbados, West Indies by a single surgeon. The mean age is 21.9 years (range 3-66 years). Seven out of 46 lesions were recurrent lesions following previous surgery. All the lesions were excised surgically (e...

INTRODUCTION The appearance of vascular anomalies in the orofacial area is a common condition, which represents about 50% of these malformations. Traditional treatment approach, such as surgery and chemical sclerosis has been given way to a few less-invasive options, as the use of the 810 nm diode laser to induce the sclerosis of the venous malformation by intralesional photocoagulation. OBJE...

OBJECTIVES To continue assessment of the benefits and risks of intralesional administration of cidofovir, an acyclic nucleoside phosphonate, for treating severe recurrent respiratory papillomatosis (RRP) in pediatric patients, and to discuss guidelines for larger prospective multi-institutional studies of the use of cidofovir. DESIGN Prospective case series. SETTING Tertiary care children's...

ten at an appropriate literacy level to ensure maximum comprehension. Other nonpharmacologic adherence strategies include empowering support staff to provide face-to-face patient counseling, which will likely lead to increased adherence and save physicians’ time. Another strategy is encouraging patients to self-monitor medication adherence. Asking patients to keep a medication diary and bring b...

OBJECTIVE To determine the efficacy of antiviral agents for recurrent respiratory papillomatosis (RRP) in children and adults. STUDY DESIGN Systematic review to include randomized controlled trials (RCTs), comparative studies (historical and/or nonrandomized), case series, and case reports. RESULTS Twenty-six original studies were included (one case-control series, 21 noncomparative trials,...