Purpose: Comparing the effects of manipulating senses on relative phase transition bimanual coordination pattern of active and inactive women with Multiple Sclerosis (MS). Methods: The methodology of this study was repeated-measures design. Study participants comprised 10 active women and 10 inactive women with multiple sclerosis who voluntarily participated in this experiment. The participant...

For a system to qualify as quantum fluid, quantum-statistical effects should operate in addition quantum-mechanical ones. Here, we address the hitherto unexplored dynamical condition for be manifested, and consider particle exchange events gaslike regime of fluid dynamics process with an intrinsic time scale. We subsequently propose quantitative criterion indistinguishability associated statist...

Fast inactivation of the HERG potassium channel plays a critical role in normal cardiac function. Malfunction of these channels due to either genetic mutations or blockade by drugs leads to cardiac arrhythmias. An unusually long S5-P linker in the outer mouth of HERG is implicated in the fast inactivation mechanism. To examine the role of the S5-P linker in this inactivation mechanism, we study...

The epidermal growth factor receptor (EGFR) is a key protein in cellular signaling, and its kinase domain (EGFR kinase) is an intensely pursued target of small-molecule drugs. Although both catalytically active and inactive conformations of EGFR kinase have been resolved crystallographically, experimental characterization of the transitions between these conformations remains difficult. Using u...

knee osteoarthritis can have negative effects on the physical and mental conditions, social and family relations, general health and positive feelings of elders. for example, severe limitation of motion and increased depression, which are results of this disease, can have negative impacts on elders. the purpose of this study was to compare the levels of depression in healthy active and inactive...

Knee osteoarthritis can have negative effects on the physical and mental conditions, social and family relations, general health and positive feelings of elders. For example, severe limitation of motion and increased depression, which are results of this disease, can have negative impacts on elders. The purpose of this study was to compare the levels of depression in healthy active and inactive...

aging is a crucial period in human life and it is a social necessity to pay attention to the issues and needs of this stage of life. the aim of the current study was to study the effect of body mass index (bmi) on reaction time and response time of the active and inactive elderly. the research method was causal-comparative and its statistical population consisted of the elderly from mahabad cit...

RIG-I and MDA5 are cytoplasmic RNA sensors that recognize dsRNA patterns and activate MAVS to induce innate antiviral gene program. RNA sensing is regulated by ubiquitination in RIG-I while by phosphorylation in MDA5. Thus, de novo phosphorylation is an essential step for keeping MDA5 inactive. We identified a protein kinase RIO kinase 3 (RIOK3) targeting MDA5, and here discuss its possible rel...

BACKGROUND 25(OH) vitamin D levels may be low in patients with moderately or severely active inflammatory bowel diseases (IBD: Crohn's disease and Idiopathic Ulcerative Colitis) but this is less clear in patients with mild or inactive IBD. Furthermore there is limited information of any family influence on 25(OH) vitamin D levels in IBD. As a possible risk factor we hypothesize that vitamin D l...