Among candidate antigens for human immunodeficiency virus (HIV) prophylactic vaccines, the regulatory protein Tat is a critical early target, but has a potential for immune suppression. Adenovirus (Ad) recombinants encoding wild-type HIV Tat (Tat-wt) and a transdominant negative mutant HIV Tat (Tat22) were constructed and administered to mice separately or together with Ad-SIVgag. Immunogenicit...

Chromium is one of main pollution in sea water, and the establishment detecting kit research hot topic. In this study, immunized mice were obtained by immunogen Cr 3+ -EDTA-BSA, hybridoma strains that secrete -EDTA monoclonal antibody selected. mAb prepared with vivo method. Then, Cr-kit for measurement chromium was developed, its application executed water seafood. Two A321 A424 screened. The ...

Background & Objectives: Due to the importance of Pseudomonas aeruginosa in severe inpatient infections and high mortality, the need for an efficient vaccine against these bacteria is increasing. In this regard, the general outer membrane porin of the most problematic microorganism P. aeruginosa, outer membrane protein F (OprF), is a good vaccine cand...