Background: BK virus, a human polyomavirus, causes nephropathy and allograft loss in renal transplant recipients. Although it was discovered 1971, understanding of the humoral immune response to BKV is limited.
 Objective: To serological detection level estimation anti-BK-IgG renal-transplanted recipients healthy blood donors as control.
 Patients Methods: Serum samples were collected...

Mycobacterium tuberculosis-specific antibodies possess immunomodulatory effects during tuberculosis infection. Prior sensitization to environmental mycobacteria is known to suppress immune responses against BCG and M. tuberculosis. Mycobacteria-induced antibodies can influence events such as complement activation and phagocytosis during infectious process. In the present study role of anti-M. t...

specific antibody deficiency lias been recognized as an immunodeficiency. in order to investigate an antipolysaccliaride antibody defect as a cause of rcccttrent infections, 30 children were studied. patients who had been identified to have a major immunodeficiency or structural abnormality or a disease known to cause infection were excluded. tliirty patints, aged i to 13.8 years (mean age, 5.8...

Specific IgG, passively administered together with particulate antigen, can completely prevent induction of antibody responses to this antigen. The ability of IgG to suppress antibody responses to sheep red blood cells (SRBCs) is intact in mice lacking FcγRs, complement factor 1q, C3, or complement receptors 1 and 2, suggesting that Fc-dependent effector functions are not involved. Two of the m...

Abstract We assessed the duration and baseline determinants of antibody responses to SARS-CoV-2 spike antigens occurrence reinfections in a prospective cohort 173 Spanish primary health care worker patients followed initially for 9 months subsequently up 12.5 after COVID-19 symptoms onset. Seropositivity receptor-binding domain 149–270 days was 92.49% (90.17% IgG, 76.3% IgA, 60.69% IgM). In sub...

We present a solid-phase immobilization method for radioligand assays, using an immunoadsorption coating procedure of anti-triiodothyronine rabbit IgG (anti-T3 IgG) onto second antibody (sheep anti-rabbit IgG) covalently bound to Amino-Dylark beads. The second antibody was in excess, compared with the first antibody, thus eliminating reproducibility problems between immunoadsorptions. Beads coa...

many different radiolabeled antibodies have been used for radioimmunotherapy and radioimmunoscintigraphy of human diseases in animal experiments. in order to study the in vivo tissue distribution of antibody, we labeled human nonspecific polyclonal igg with na125i using chloramine-t method. an animal model was developed by injecting turpentine in the posterior left thigh of balb/c mice. tissue ...

The in vivo localization of radiolabeled heterospecific antibody to carcinoembryonic antigen (CEA) was inves tigated in a human colonie tumor-hamster host model. With the paired-labeled antibody technique, a significant and specific accumulation of goat anti-CEA immunoglobulin G (IgG) was observed in small tumors (<5.0 g) l day after injection. The level of anti-CEA IgG in the tumor sub sequent...

Typhoid Vi-conjugate vaccines (Vi-TCV) have been developed to control typhoid fever in children endemic regions. Previously, a human challenge model of typhoid, Vi-TCV was administered prior deliberate ingestion Salmonella Typhi by healthy adult volunteers the UK. Vi-specific antibody-dependent neutrophil phagocytosis (ADNP) associated with protection against enteric this model, but it is not k...